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EEF1A1 and DUSP7
Data Source:
BioGRID
(two hybrid)
EEF1A1
DUSP7
Description
eukaryotic translation elongation factor 1 alpha 1
dual specificity phosphatase 7
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Nucleolus
Cytoplasm
Cytosol
Eukaryotic Translation Elongation Factor 1 Complex
Plasma Membrane
Membrane
Cortical Actin Cytoskeleton
Ruffle Membrane
Secretory Granule Lumen
Extracellular Exosome
Cytoplasmic Side Of Lysosomal Membrane
Ficolin-1-rich Granule Lumen
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
TRNA Binding
RNA Binding
Translation Elongation Factor Activity
GTPase Activity
Protein Binding
Calmodulin Binding
GTP Binding
Kinase Binding
Protein Kinase Binding
Phosphoprotein Phosphatase Activity
Protein Tyrosine Phosphatase Activity
Protein Binding
Protein Tyrosine/threonine Phosphatase Activity
MAP Kinase Tyrosine/serine/threonine Phosphatase Activity
Mitogen-activated Protein Kinase Binding
Protein Serine Phosphatase Activity
Protein Threonine Phosphatase Activity
Biological Process
Translation
Translational Elongation
Neutrophil Degranulation
Cellular Response To Epidermal Growth Factor Stimulus
Regulation Of D-erythro-sphingosine Kinase Activity
Regulation Of Chaperone-mediated Autophagy
MAPK Cascade
Activation Of MAPK Activity
Inactivation Of MAPK Activity
Protein Dephosphorylation
Peptidyl-tyrosine Dephosphorylation
Peptidyl-threonine Dephosphorylation
Negative Regulation Of MAP Kinase Activity
Pathways
Eukaryotic Translation Elongation
Eukaryotic Translation Elongation
Peptide chain elongation
HSF1 activation
Neutrophil degranulation
Protein methylation
Chaperone Mediated Autophagy
RAF-independent MAPK1/3 activation
ERKs are inactivated
Negative regulation of MAPK pathway
Signaling by MAPK mutants
Drugs
Zinc
Guanosine-5'-Diphosphate
Copper
Artenimol
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Interacting Genes
130 interacting genes:
ABTB2
ACTB
ALPL
ANKRD24
ANXA7
APLP1
AQP2
ARIH2
AXIN1
BBS1
BBS2
BBS4
BRMS1
BTBD2
CASP2
CCDC130
CCL18
CDC25A
CDKN1A
CKS2
COX17
CRADD
CRCT1
CSRP2
DARS1
DIABLO
DLEU1
DUSP7
DYNLL1
DYSF
EIF3F
EP300
EXOSC4
FAS
GADD45A
GADD45G
HSPB2
HSPE1
HTRA2
IKBKG
IMMT
ITGB1BP1
ITSN1
KCNE3
KIF1B
LAMA4
LAMTOR1
LAMTOR5
LSM3
MAD2L1BP
MAGED2
MAP3K14
MAPK14
MLLT3
MNAT1
MRM1
MRPL42
MTRNR2L1
MYOC
NEU1
NRAS
NREP
ORMDL3
PABPC4
PAEP
PAFAH1B3
PAPSS1
PCDHA4
PFN2
PHYHIP
PKN2
PLAUR
PLCG1
POLE2
POLR2C
PQBP1
PRKCD
PSG9
PSMD11
PTPN4
PTPRCAP
PTPRF
RAB27A
RAP2A
RBBP8
RFC5
RGS12
RND1
RNF10
RPA2
RPLP1
RRAS
RSRC1
SARS2
SDHAF2
SERPINB5
SERPINB9
SFN
SHBG
SMAD2
SMAD4
SMN1
SNCA
SPP1
SSR1
STAT6
STMN2
SULT1E1
SUMO2
TAF9
TGIF1
TK1
TMPRSS3
TNFSF11
TP53BP2
TPT1
TRDMT1
TSPY1
TSPYL2
TTLL12
TTR
UBQLN4
WARS1
XPO5
XRN2
YWHAG
ZBTB16
ZCCHC10
ZNF24
ZPR1
7 interacting genes:
EEF1A1
EGLN3
GHR
IL16
MAPK1
MAPK14
MAPK8
Entrez ID
1915
1849
HPRD ID
00559
04125
Ensembl ID
ENSG00000156508
ENSG00000164086
Uniprot IDs
P68104
Q6IPS9
Q16829
PDB IDs
1SYW
3C5J
6ZMO
4Y2E
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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