PHC1 and SUMO1P1

Data Source:
BioGRID (two hybrid)

		PHC1	SUMO1P1
Description		polyhomeotic homolog 1	SUMO1 pseudogene 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Nucleus PML Body
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Histone Binding	Protein Binding Transcription Factor Binding Protein Tag Identical Protein Binding Ubiquitin-like Protein Ligase Binding
	Biological Process	Multicellular Organism Development Histone Ubiquitination Negative Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition	Protein Sumoylation PML Body Organization
Pathways		Oxidative Stress Induced Senescence SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Antisaccade task score ( 31596458) Cholesterol, total ( 24097068) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Height ( 31562340) Prepulse inhibition of the startle response ( 31596458) Small cell lung carcinoma ( 28604730) Total cholesterol levels ( 28334899)	Copper levels ( 26025379) Polycystic ovary syndrome ( 22885925)
Interacting Genes		24 interacting genes: BMI1 FAM9A GMNN HSPA8 PCGF2 PCGF3 PHC2 PIAS2 PPP1CA PPP1CC RING1 RNF2 RNF4 SCMH1 SDCBP2 SFMBT1 SFMBT2 SIAH1 SP100 SUMO1 SUMO1P1 TET2 UBE2I ZCCHC7	33 interacting genes: ACTN3 AXIN1 C18orf25 CKS1B EDARADD ESRRG FAM118B FAM200A FHL2 FKBP6 GMCL1 HNRNPC KRTAP9-2 L3MBTL3 LCE2A LCE2D MAPK1IP1L NAB2 PHC1 PIAS1 PIAS2 SATB1 SETBP1 SOX5 STX1A SUMO1 TRAF2 TRIM23 UBA2 UBE2I ZBTB26 ZBTB6 ZNRD2
Entrez ID		1911	391257
HPRD ID		16009
Ensembl ID		ENSG00000111752
Uniprot IDs		P78364 Q6GMQ3 Q6N083
PDB IDs		2L8E
Enriched GO Terms of Interacting Partners?
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