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DVL3 and MAGOHB
Data Source:
BioGRID
(two hybrid)
DVL3
MAGOHB
Description
dishevelled segment polarity protein 3
mago homolog B, exon junction complex subunit
Image
GO Annotations
Cellular Component
Chromatin
Cytosol
Nucleus
Nucleoplasm
Exon-exon Junction Complex
Neuronal Cell Body
U2-type Precatalytic Spliceosome
U2-type Catalytic Step 1 Spliceosome
Catalytic Step 2 Spliceosome
Molecular Function
Protease Binding
Signaling Receptor Binding
Frizzled Binding
Protein Binding
Beta-catenin Binding
Small GTPase Binding
RNA Binding
Protein Binding
Biological Process
Positive Regulation Of Protein Phosphorylation
Intracellular Signal Transduction
Non-canonical Wnt Signaling Pathway
Non-canonical Wnt Signaling Pathway Via JNK Cascade
Response To Drug
Positive Regulation Of JUN Kinase Activity
Positive Regulation Of GTPase Activity
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Protein Stabilization
Canonical Wnt Signaling Pathway
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Negative Regulation Of Canonical Wnt Signaling Pathway
Planar Cell Polarity Pathway Involved In Neural Tube Closure
Positive Regulation Of Neuron Projection Arborization
Regulation Of Cellular Protein Localization
Beta-catenin Destruction Complex Disassembly
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
MRNA Splicing, Via Spliceosome
RNA Export From Nucleus
MRNA Export From Nucleus
RNA Splicing
MRNA 3'-end Processing
Pathways
TCF dependent signaling in response to WNT
WNT mediated activation of DVL
PCP/CE pathway
PCP/CE pathway
Degradation of DVL
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Negative regulation of TCF-dependent signaling by DVL-interacting proteins
RHO GTPases Activate Formins
WNT5:FZD7-mediated leishmania damping
WNT5:FZD7-mediated leishmania damping
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Facial morphology traits (63 three-dimensional facial segments) (
29459680
)
Major depressive disorder (
22472876
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Interacting Genes
164 interacting genes:
ABT1
ADAP1
AKAP17A
ANKRD36B
AP3M1
AXIN1
BAHD1
BEND7
BHLHE40
C1orf35
C8orf33
CBX8
CCDC33
CCNK
CCNL1
CDYL2
CEP57L1
CEP70
CEP76
CLK1
CSNK1D
CSNK1E
CSNK2A1
CT45A10
CT45A3
CTNNB1
CYSRT1
DAB2
DDX54
DIDO1
DPPA2
DVL1
EIF1B
EIF3D
ENKD1
FAM13C
FAM90A1
FARS2
FGF16
FLACC1
GADD45GIP1
HOMER3
HOXA5
HOXC5
HOXC8
INO80B
KAT7
KAZN
KCTD10
KCTD7
KLF1
KLF15
KLF3
KLF4
KLHL12
LENG8
LNX1
LONRF1
LRRK2
LUZP4
LY6H
MAB21L3
MAGEB4
MAGOHB
MARK2
MATN2
NFYA
NKD1
NOL12
NXF1
PATZ1
PHF19
PIK3CB
PITX1
PLAGL2
PLN
PNKP
PPM1A
PPP1R16B
PPP2CA
PRKAA2
PRPF18
PRPF3
PRPF31
PRPF38A
PRR13
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSME3
PSMF1
RBM15B
RBM39
RNF151
RPL11
RPS10
RRP8
RWDD2B
SAP30L
SHFL
SNIP1
SNX22
SORBS3
STOM
SUV39H1
SYT6
SYTL4
TBPL1
TCEA2
TCEANC
TFG
THAP7
TLE5
TNFAIP8L1
TNP1
TPTEP2-CSNK1E
TRAF2
TRIM41
TRIM54
TSN
TSPYL1
TSPYL6
UTP3
VANGL1
VAX1
WDR25
WT1
XPA
YTHDC1
ZBTB24
ZBTB26
ZBTB47
ZBTB48
ZBTB8A
ZFP57
ZNF165
ZNF2
ZNF264
ZNF319
ZNF408
ZNF417
ZNF441
ZNF444
ZNF497
ZNF512B
ZNF552
ZNF581
ZNF648
ZNF696
ZNF697
ZNF699
ZNF71
ZNF764
ZNF774
ZNF775
ZNF792
ZNF821
ZNF837
ZRSR2
ZSCAN21
ZSCAN22
ZSCAN25
73 interacting genes:
ADAMTSL4
AMOTL2
BEND7
C18orf54
CALCOCO2
CARD10
CCDC102B
CCDC106
CCDC33
DVL2
DVL3
EFHC2
FHL5
FXR1
GNPDA2
GOLGA2
GPANK1
HMG20A
HSF2BP
IHO1
IKZF1
IKZF3
INCA1
KRT40
KRT75
KRTAP1-1
KRTAP13-2
MID2
NDUFB7
PARD6B
PAX7
PBX4
PKP2
PRPH
PRPSAP1
PTPN21
RBAK
RBM8A
RBMX
REL
RUNDC3A
SNW1
SPATA6
SPDYE4
STX11
TADA2A
TCF4
TERF2
TERF2IP
THAP7
TLE5
TRA2A
TRA2B
TRIM27
TRIM42
YWHAG
ZBTB10
ZBTB42
ZFP14
ZFYVE1
ZNF19
ZNF250
ZNF398
ZNF426
ZNF438
ZNF446
ZNF449
ZNF547
ZNF566
ZNF57
ZNF620
ZNF774
ZNF835
Entrez ID
1857
55110
HPRD ID
03222
08544
Ensembl ID
ENSG00000161202
ENSG00000111196
Uniprot IDs
Q92997
Q9UG07
A0A023T6R1
F5H6P7
Q96A72
PDB IDs
6V7O
5XJC
5YZG
6ICZ
6QDV
Enriched GO Terms of Interacting Partners
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