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AFP and PHB2
Data Source:
BioGRID
(two hybrid)
AFP
PHB2
Description
alpha fetoprotein
prohibitin 2
Image
GO Annotations
Cellular Component
Extracellular Space
Cytoplasm
Endoplasmic Reticulum Lumen
Nucleus
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane
Mitochondrial Inner Membrane
Plasma Membrane
Cell Surface
Postsynaptic Density
Nuclear Matrix
Axon
Protein-containing Complex
Mitochondrial Prohibitin Complex
Presynaptic Active Zone
Cell Periphery
Glutamatergic Synapse
GABA-ergic Synapse
Molecular Function
Fatty Acid Binding
Protein Binding
Zinc Ion Binding
Protein Binding
Protein C-terminus Binding
Estrogen Receptor Binding
Amide Binding
Identical Protein Binding
Protein Homodimerization Activity
Sphingolipid Binding
Protein Heterodimerization Activity
Protein N-terminus Binding
Biological Process
Transport
Post-translational Protein Modification
Cellular Protein Metabolic Process
Activation Of MAPK Activity
Mitophagy
Immunoglobulin Production
Protein Import Into Nucleus
Mitochondrial Calcium Ion Transmembrane Transport
Mitochondrion Organization
Sister Chromatid Cohesion
Activation Of Phospholipase C Activity
Response To Wounding
Cell Migration
CD40 Signaling Pathway
Regulation Of Complement Activation
Positive Regulation Of Exit From Mitosis
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Negative Regulation Of Mammary Gland Epithelial Cell Proliferation
Induction By Virus Of Host Autophagy
RIG-I Signaling Pathway
B Cell Activation
Negative Regulation Of Apoptotic Process
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of Transcription, DNA-templated
Protein Stabilization
Positive Regulation Of DNA-binding Transcription Factor Activity
Mammary Gland Branching Involved In Thelarche
Mammary Gland Alveolus Development
Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Retinoic Acid
Cellular Response To Hypoxia
Antiviral Innate Immune Response
Regulation Of Cardiolipin Metabolic Process
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Cytochrome-c Oxidase Activity
Activation Of Protein Kinase C Activity
Pathways
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
Processing of SMDT1
Drugs
Capsaicin
Rocaglamide
Didesmethylrocaglamide
Diseases
GWAS
Blood protein levels (
30072576
)
Prostate cancer (
23535732
)
Tumor biomarkers (
23300138
)
Glycated hemoglobin levels (
28898252
)
Red blood cell fatty acid levels (
25500335
)
Refractive error (
32231278
)
Interacting Genes
14 interacting genes:
AP4S1
CASP3
CCR5
CREBBP
EHD4
GNB1
MED27
PHB2
PIDD1
PSMB7
PTEN
SGSM2
SIRT1
XIAP
21 interacting genes:
AFP
AKT1
CDC42
ESR1
EZH2
FHL2
HDAC1
HDAC2
HDAC3
HDAC5
MEF2A
MYOD1
NR2F1
NR2F2
PPARG
PRKCA
PTEN
PTMA
RNF2
TEAD3
UPF2
Entrez ID
174
11331
HPRD ID
00074
17843
Ensembl ID
ENSG00000081051
ENSG00000215021
Uniprot IDs
P02771
Q99623
PDB IDs
3MRK
6IQE
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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