AFP and AP4S1

		AFP	AP4S1
Description		alpha fetoprotein	adaptor related protein complex 4 subunit sigma 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Endoplasmic Reticulum Lumen	AP-4 Adaptor Complex Endosome Lumen Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Fatty Acid Binding Protein Binding Zinc Ion Binding
	Biological Process	Transport Post-translational Protein Modification Cellular Protein Metabolic Process	Protein Targeting Protein Localization Vesicle-mediated Transport
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Lysosome Vesicle Biogenesis
Drugs
Diseases			Cerebral palsy
GWAS		Blood protein levels ( 30072576) Prostate cancer ( 23535732) Tumor biomarkers ( 23300138)	Brain morphology (MOSTest) ( 32665545) Mean corpuscular volume ( 32888494)
Interacting Genes		14 interacting genes: AP4S1 CASP3 CCR5 CREBBP EHD4 GNB1 MED27 PHB2 PIDD1 PSMB7 PTEN SGSM2 SIRT1 XIAP	6 interacting genes: AFP APP GRB2 GTF2I HTR6 TEAD3
Entrez ID		174	11154
HPRD ID		00074	06257
Ensembl ID		ENSG00000081051	ENSG00000100478
Uniprot IDs		P02771	Q9Y587
PDB IDs		3MRK
Enriched GO Terms of Interacting Partners?
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