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DBN1 and SUPT5H
Data Source:
HPRD
(two hybrid)
DBN1
SUPT5H
Description
drebrin 1
SPT5 homolog, DSIF elongation factor subunit
Image
GO Annotations
Cellular Component
Cytoplasm
Cytoskeleton
Actin Filament
Plasma Membrane
Gap Junction
Postsynaptic Density
Actin Cytoskeleton
Lamellipodium
Dendrite
Growth Cone
Site Of Polarized Growth
Cortical Cytoskeleton
Cortical Actin Cytoskeleton
Actomyosin
Postsynaptic Membrane
Glutamatergic Synapse
Postsynaptic Cytosol
Nucleus
Nucleoplasm
DSIF Complex
Molecular Function
Actin Binding
Protein Binding
Profilin Binding
Cadherin Binding
Actin Filament Binding
Chromatin Binding
RNA Binding
MRNA Binding
Protein Binding
Enzyme Binding
Protein Heterodimerization Activity
Biological Process
In Utero Embryonic Development
Actin Filament Organization
Cell Communication By Chemical Coupling
Cell Communication By Electrical Coupling
Regulation Of Actin Filament Polymerization
Positive Regulation Of Synaptic Plasticity
Maintenance Of Protein Location In Cell
Positive Regulation Of Axon Extension
Regulation Of Neuronal Synaptic Plasticity
Neuron Projection Morphogenesis
Regulation Of Dendrite Development
Cytoplasmic Sequestering Of Protein
Positive Regulation Of Dendritic Spine Morphogenesis
Neural Precursor Cell Proliferation
Postsynaptic Actin Cytoskeleton Organization
Positive Regulation Of Receptor Localization To Synapse
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Positive Regulation Of Macroautophagy
Negative Regulation Of DNA-templated Transcription, Elongation
Positive Regulation Of DNA-templated Transcription, Elongation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Viral Transcription
Negative Regulation Of MRNA Polyadenylation
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
RNA Polymerase II Transcription Elongation
RNA Pol II CTD phosphorylation and interaction with CE
Drugs
Diseases
GWAS
Activated partial thromboplastin time (
22703881
)
Extremely high intelligence (
29520040
)
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI (age <50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Neutrophil count (
32888494
)
White blood cell count (
32888494
)
Interacting Genes
27 interacting genes:
ACD
BAK1
BTRC
CDK2AP2
DNMBP
DUSP23
ESR1
FHL1
HOMER2
MAP1LC3B
MAPK6
MEST
NIPBL
NUDT21
NUDT3
PFN1
POT1
PTEN
RABGAP1L
SNUPN
SUPT5H
TAB1
TERF1
TINF2
TPT1
UBE2D3
ZNF598
45 interacting genes:
C9orf78
CCNH
CCNT1
CCNT2
CDK7
CDK9
CEP55
CSNK2A1
DBN1
DCAF6
FHL3
GOLGA2
GTF3C1
H2AX
HSPB1
HTATSF1
IK
IKBKG
LMAN2
MAD1L1
MAML3
MNAT1
PCBD1
PHYHIP
PIN1
PNO1
POLR2A
PPIA
PPP2R2D
PRMT1
PRMT5
SAP30BP
SIK1
SNX4
SSBP3
SUMO2
SUPT4H1
TERF1
TEX11
TLE5
XRCC5
ZBTB3
ZFYVE9
ZNF496
ZNF512B
Entrez ID
1627
6829
HPRD ID
00545
03655
Ensembl ID
ENSG00000113758
ENSG00000196235
Uniprot IDs
Q16643
O00267
PDB IDs
5Y1Z
5ZZ9
2DO3
2E6Z
2E70
3H7H
4L1U
5OHO
5OHQ
5OIK
5U98
6EQY
6ER0
6GMH
6GML
6TED
Enriched GO Terms of Interacting Partners
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