DPPA2 and FGF12

Data Source:
BioGRID (two hybrid)

		DPPA2	FGF12
Description		developmental pluripotency associated 2	fibroblast growth factor 12
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Extracellular Space Nucleus Cytoplasm Synapse
	Molecular Function	Chromatin Binding Protein Binding	Protein Binding Growth Factor Activity Sodium Channel Regulator Activity Ion Channel Binding
	Biological Process	System Development	Regulation Of Membrane Depolarization Signal Transduction Cell-cell Signaling Chemical Synaptic Transmission Nervous System Development Heart Development Adult Locomotory Behavior Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Sodium Ion Transport Neuromuscular Process Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Neuronal Action Potential Regulation Of Sodium Ion Transmembrane Transport Regulation Of Voltage-gated Sodium Channel Activity Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Cation Channel Activity
Pathways			Phase 0 - rapid depolarisation
Drugs
Diseases
GWAS		Corneal astigmatism ( 23761726) Spatial memory ( 31596458)	Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Bipolar disorder ( 31043756) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) Hip circumference adjusted for BMI ( 28552196) Idiopathic dilated cardiomyopathy ( 29495422) Ileal carcinoids ( 21139019) Major depressive disorder ( 23377640) Metabolite levels ( 19043545) Post bronchodilator FEV1/FVC ratio ( 26634245) PR interval ( 32439900) Serum metabolite concentrations in chronic kidney disease ( 29545352) Severe influenza A (H1N1) infection ( 26379185) Sleep quality ( 23728906)
Interacting Genes		19 interacting genes: AP2M1 DPPA4 DVL2 DVL3 EIF1AD FGF12 FXR2 MCM10 MOAP1 PBXIP1 PLOD3 SDCBP2 SETD5 SPOP U2AF2 UBE2I VTA1 ZCCHC10 ZNF250	25 interacting genes: APP COIL CT45A1 DACH1 DCTD DPPA2 GRIP1 IKZF1 LZTS2 MAPK13 MAPK8IP2 NEDD4 NEDD4L PJA1 RBAK RNF151 RP9 SMURF1 SRPK1 SRPK2 STAC3 THAP1 YWHAE ZNF460 ZNF79
Entrez ID		151871	2257
HPRD ID		13248	03303
Ensembl ID		ENSG00000163530	ENSG00000114279
Uniprot IDs		Q7Z7J5	P61328
PDB IDs			1Q1U 4JQ0
Enriched GO Terms of Interacting Partners?
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