FGF12 and RP9

Data Source:
BioGRID (two hybrid)

		FGF12	RP9
Description		fibroblast growth factor 12	RP9 pre-mRNA splicing factor
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Synapse	Nucleus Signal Recognition Particle Receptor Complex
	Molecular Function	Protein Binding Growth Factor Activity Sodium Channel Regulator Activity Ion Channel Binding	RNA Binding Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Membrane Depolarization Signal Transduction Cell-cell Signaling Chemical Synaptic Transmission Nervous System Development Heart Development Adult Locomotory Behavior Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Sodium Ion Transport Neuromuscular Process Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Neuronal Action Potential Regulation Of Sodium Ion Transmembrane Transport Regulation Of Voltage-gated Sodium Channel Activity Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Cation Channel Activity	RNA Splicing Cognition
Pathways		Phase 0 - rapid depolarisation
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Bipolar disorder ( 31043756) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) Hip circumference adjusted for BMI ( 28552196) Idiopathic dilated cardiomyopathy ( 29495422) Ileal carcinoids ( 21139019) Major depressive disorder ( 23377640) Metabolite levels ( 19043545) Post bronchodilator FEV1/FVC ratio ( 26634245) PR interval ( 32439900) Serum metabolite concentrations in chronic kidney disease ( 29545352) Severe influenza A (H1N1) infection ( 26379185) Sleep quality ( 23728906)
Interacting Genes		25 interacting genes: APP COIL CT45A1 DACH1 DCTD DPPA2 GRIP1 IKZF1 LZTS2 MAPK13 MAPK8IP2 NEDD4 NEDD4L PJA1 RBAK RNF151 RP9 SMURF1 SRPK1 SRPK2 STAC3 THAP1 YWHAE ZNF460 ZNF79	10 interacting genes: AP1M1 APP BYSL C1orf35 CIR1 FGF12 NKAPD1 SDCBP SREK1IP1 U2AF1
Entrez ID		2257	6100
HPRD ID		03303	08457
Ensembl ID		ENSG00000114279	ENSG00000164610
Uniprot IDs		P61328	A0A090N8Z0 Q8TA86
PDB IDs		1Q1U 4JQ0
Enriched GO Terms of Interacting Partners?
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