CSNK1G2 and PPP1R14A

Data Source:
HPRD (in vitro)

		CSNK1G2	PPP1R14A
Description		casein kinase 1 gamma 2	protein phosphatase 1 regulatory inhibitor subunit 14A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Cell Cortex Membrane	Cytosol
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Serine/threonine Phosphatase Inhibitor Activity
	Biological Process	Protein Phosphorylation Endocytosis Signal Transduction Wnt Signaling Pathway Peptidyl-serine Phosphorylation Sphingolipid Biosynthetic Process Protein Autophosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway	Negative Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Phosphorylation
Pathways		Sphingolipid de novo biosynthesis Disassembly of the destruction complex and recruitment of AXIN to the membrane	RHO GTPases activate PKNs
Drugs		IC261 N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide 5-iodotubercidin
Diseases
GWAS		Body mass index ( 25673413) Coronary artery disease ( 29212778) Red cell distribution width ( 32888494 27863252)	Diverticular disease ( 30177863)
Interacting Genes		14 interacting genes: APP APPBP2 CERT1 DBNDD2 IRS4 KRTAP10-7 MTA1 NCK1 PER1 PPP1R14A RAP1GAP RUNDC3B SMAD3 WDCP	16 interacting genes: APP CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 DAPK1 PRKCA PRKCE PRKCG PRKCH PRKCZ PRKD1 PRNP YWHAZ
Entrez ID		1455	94274
HPRD ID		03738	16291
Ensembl ID		ENSG00000133275	ENSG00000167641
Uniprot IDs		P78368	Q96A00
PDB IDs		2C47
Enriched GO Terms of Interacting Partners?
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