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CRX and OSTF1
Data Source:
BioGRID
(two hybrid)
CRX
OSTF1
Description
cone-rod homeobox
osteoclast stimulating factor 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
RNA Polymerase II Transcription Regulator Complex
Extracellular Region
Intracellular Anatomical Structure
Secretory Granule Lumen
Ficolin-1-rich Granule Lumen
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Transcription Factor Binding
DNA-binding Transcription Activator Activity
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Nuclear Hormone Receptor Binding
Leucine Zipper Domain Binding
Sequence-specific Double-stranded DNA Binding
Protein Binding
SH3 Domain Binding
Biological Process
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Visual Perception
Animal Organ Morphogenesis
Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Response To Stimulus
Ossification
Signal Transduction
Neutrophil Degranulation
Pathways
Neutrophil degranulation
Drugs
Diseases
Leber congenital amaurosis (LCR)
Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS
Allergic rhinitis (
25085501
)
Glucose homeostasis traits (
25524916
)
Loneliness (
29970889
)
Loneliness (MTAG) (
29970889
)
Resting-state electroencephalogram vigilance (
29703947
)
Systemic sclerosis (
30247649
)
Urinary magnesium-to-creatinine ratio (
29093028
)
Interacting Genes
112 interacting genes:
AASDHPPT
ABI2
ACBD4
ARIH2
ATG12
ATM
ATP6V0D2
ATXN1
ATXN7
BANF1
BANF2
BANP
BOD1L2
C19orf25
C1orf109
C1orf50
C1orf56
C9orf72
CA8
CCNC
CDKN2C
CFAP206
CREBBP
CSNK1G2-AS1
CTNNA3
DELE1
EIF5A
EP300
FAAP20
FOXH1
GCM2
GLIS2
GUCD1
GYS1
HGS
HNF1B
IGFN1
IPO13
IRX6
KANK2
KAT2A
KLHL32
LARP4
LGALS3
LIMS3
LIMS4
LNX1
LONRF1
M1AP
MDFI
MLLT6
MYO15B
MYOZ1
NEIL2
NFYC
NIP7
NPAS2
NR2E3
NRL
NTF4
OR6B1
OSGIN1
OSTF1
PDC
PICALM
PID1
PNMA6A
POGZ
PPP1R16B
PRKAB2
PRKN
PRR35
PSMA1
PSMB10
PSMF1
QRICH1
RAX2
RBFOX1
RBPMS
RHOXF2
ROR2
SAE1
SDCBP
SEC14L4
SFI1
SMAD3
SMAP1
SMAP2
SMUG1
SOX10
SOX14
SOX3
SOX5
SPG21
STK16
SUFU
SUOX
SZT2
TBX6
TCF7L2
TEX33
TFG
TLE5
TLX3
TNS2
UBXN2B
UBXN7
VPS37C
ZC3H10
ZIC1
ZNF483
ZNF688
51 interacting genes:
AGR2
APP
BORCS6
CBL
CBLB
CCDC33
CRX
CTDSP1
CUEDC1
DPPA4
DTX3
EFS
ERRFI1
FASLG
FBXO7
GAPDH
GGN
HES7
HTT
KHDRBS1
KLHL42
LATS1
LMNA
MAPK6
MED19
MEOX2
NFYC
NUTM1
NUTM2F
PBX4
PICK1
REL
RP2
SDCBP
SF1
SF3A2
SMN1
SNW1
SOCS7
SYNGAP1
TRIB3
TRIM54
VPS37B
WASF1
WASHC1
WASL
YPEL3
ZBTB42
ZBTB7B
ZNF655
ZNF688
Entrez ID
1406
26578
HPRD ID
03748
17808
Ensembl ID
ENSG00000105392
ENSG00000134996
Uniprot IDs
O43186
Q92882
PDB IDs
1X2K
1ZLM
3EHQ
3EHR
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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