CLVS2 and S100A7

Data Source:
BioGRID (two hybrid)

		CLVS2	S100A7
Description		clavesin 2	S100 calcium binding protein A7
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Trans-Golgi Network Clathrin-coated Vesicle Early Endosome Membrane Trans-Golgi Network Membrane	Extracellular Region Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Focal Adhesion Azurophil Granule Lumen Collagen-containing Extracellular Matrix
	Molecular Function	Protein Binding Phosphatidylinositol-3,5-bisphosphate Binding Phosphatidylinositol Bisphosphate Binding	Calcium Ion Binding Protein Binding Zinc Ion Binding Calcium-dependent Protein Binding RAGE Receptor Binding
	Biological Process	Lysosome Organization	Response To Reactive Oxygen Species Angiogenesis Epidermis Development Positive Regulation Of T Cell Chemotaxis Antimicrobial Humoral Response Keratinocyte Differentiation Response To Lipopolysaccharide Neutrophil Degranulation Innate Immune Response Defense Response To Gram-negative Bacterium Sequestering Of Metal Ion Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Granulocyte Chemotaxis Positive Regulation Of Monocyte Chemotaxis
Pathways		Lysosome Vesicle Biogenesis	Neutrophil degranulation Metal sequestration by antimicrobial proteins
Drugs			Ibuprofen Zinc 8-anilinonaphthalene-1-sulfonic acid Dexibuprofen Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Refractive error ( 32231278)	Blood protein levels ( 30072576)
Interacting Genes		16 interacting genes: EMSY FBXW2 FLAD1 GSTM3 GSTZ1 GYS1 KAZN MEOX2 MYH7 PAFAH1B2 PCYT2 PGAM2 PHETA2 S100A7 S100A7A TACC2	8 interacting genes: CLVS2 COPS5 EGFR FABP5 RANBP9 S100A7L2 TGM2 UCHL5
Entrez ID		134829	6278
HPRD ID		16666	02645
Ensembl ID		ENSG00000146352	ENSG00000143556
Uniprot IDs		Q5SYC1	P31151
PDB IDs			1PSR 2PSR 2WND 2WOR 2WOS 3PSR 4AQJ
Enriched GO Terms of Interacting Partners?
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