CLVS2 and GYS1

Data Source:
BioGRID (two hybrid)

		CLVS2	GYS1
Description		clavesin 2	glycogen synthase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Trans-Golgi Network Clathrin-coated Vesicle Early Endosome Membrane Trans-Golgi Network Membrane	Cytoplasm Cytosol Membrane Inclusion Body
	Molecular Function	Protein Binding Phosphatidylinositol-3,5-bisphosphate Binding Phosphatidylinositol Bisphosphate Binding	Glycogen (starch) Synthase Activity Protein Binding Glucose Binding Protein Kinase Binding Glycogen Synthase Activity, Transferring Glucose-1-phosphate
	Biological Process	Lysosome Organization	Glycogen Biosynthetic Process Heart Development
Pathways		Lysosome Vesicle Biogenesis	Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1)
Drugs
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		Refractive error ( 32231278)
Interacting Genes		16 interacting genes: EMSY FBXW2 FLAD1 GSTM3 GSTZ1 GYS1 KAZN MEOX2 MYH7 PAFAH1B2 PCYT2 PGAM2 PHETA2 S100A7 S100A7A TACC2	43 interacting genes: AIMP2 APP BEND7 CCDC33 CDCA8 CLVS2 CRX CSNK2A1 EFHC2 FAM228A GSK3B GYG1 GYG2 HOXB6 HOXC8 IHO1 INCA1 KATNBL1 KLF1 KLF4 MAPKAPK5 MEOX1 NDUFB7 NHLRC1 PCYT1A PINX1 PLAGL2 PNMA5 PRKACA RBM48 SNIP1 SORBS3 SUMO2 TFAP2D TLE5 WASHC1 ZBTB33 ZNF212 ZNF326 ZNF474 ZNF552 ZNF620 ZNF774
Entrez ID		134829	2997
HPRD ID		16666	00721
Ensembl ID		ENSG00000146352	ENSG00000104812
Uniprot IDs		Q5SYC1	P13807
PDB IDs
Enriched GO Terms of Interacting Partners?
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