SLC31A2 and RAMP3

Data Source:
BioGRID (pull down)

		SLC31A2	RAMP3
Description		solute carrier family 31 member 2	receptor activity modifying protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Late Endosome Plasma Membrane Integral Component Of Plasma Membrane Recycling Endosome	Lysosome Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex Amylin Receptor Complex 3 Adrenomedullin Receptor Complex
	Molecular Function	Copper Ion Transmembrane Transporter Activity Protein Binding	Amyloid-beta Binding Adrenomedullin Receptor Activity Protein Binding Coreceptor Activity Amylin Receptor Activity
	Biological Process	Copper Ion Transport Cellular Copper Ion Homeostasis Copper Ion Transmembrane Transport Regulation Of Copper Ion Transmembrane Transport	Angiogenesis Positive Regulation Of Receptor Recycling Calcium Ion Transport Intracellular Protein Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Gene Expression Positive Regulation Of Protein Kinase A Signaling Positive Regulation Of Cell Death Protein Transport Receptor Internalization Cellular Response To Hormone Stimulus Positive Regulation Of Peptidyl-serine Phosphorylation Cross-receptor Inhibition Within G Protein-coupled Receptor Heterodimer Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Estradiol Stimulus Protein Localization To Plasma Membrane G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Amylin Receptor Signaling Pathway Positive Regulation Of Protein Localization To Plasma Membrane Response To Amyloid-beta Positive Regulation Of Calcium Ion Import Across Plasma Membrane Adrenomedullin Receptor Signaling Pathway
Pathways			G alpha (s) signalling events Calcitonin-like ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs			Pramlintide
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil count ( 32888494)	Hepatic lipid content in extreme obesity ( 25246029)
Interacting Genes		9 interacting genes: BNIP3 F2RL1 GPR35 HTR2B OPRL1 RAMP1 RAMP2 RAMP3 VKORC1	15 interacting genes: CALCR CALCRL CYSRT1 HSPB3 KRTAP10-3 KRTAP5-3 KRTAP5-7 KRTAP5-9 KRTAP9-3 NBPF19 NOTCH2NLA NSF PDCD6IP SLC31A2 VIPR1
Entrez ID		1318	10268
HPRD ID		04365	05517
Ensembl ID		ENSG00000136867	ENSG00000122679
Uniprot IDs		O15432 Q53X94	A4D2L1 O60896
PDB IDs			6UUS 6UVA
Enriched GO Terms of Interacting Partners?
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