SLC31A2 and RAMP2

Data Source:
BioGRID (pull down)

		SLC31A2	RAMP2
Description		solute carrier family 31 member 2	receptor activity modifying protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Late Endosome Plasma Membrane Integral Component Of Plasma Membrane Recycling Endosome	Cytoplasm Lysosome Plasma Membrane Integral Component Of Plasma Membrane Clathrin-coated Pit Cell Surface Receptor Complex Amylin Receptor Complex 2 Adrenomedullin Receptor Complex
	Molecular Function	Copper Ion Transmembrane Transporter Activity Protein Binding	Adrenomedullin Receptor Activity Protein Binding Coreceptor Activity Amylin Receptor Activity Adrenomedullin Binding
	Biological Process	Copper Ion Transport Cellular Copper Ion Homeostasis Copper Ion Transmembrane Transport Regulation Of Copper Ion Transmembrane Transport	Angiogenesis Vasculogenesis Response To Hypoxia Sprouting Angiogenesis Calcium Ion Transport Intracellular Protein Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Heart Development Female Pregnancy Regulation Of Blood Pressure Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Gene Expression Protein Transport Receptor Internalization Positive Regulation Of Protein Binding Response To Estradiol Response To Progesterone Cellular Response To Hormone Stimulus Adherens Junction Assembly Cellular Response To Vascular Endothelial Growth Factor Stimulus Negative Regulation Of Vascular Permeability Positive Regulation Of Angiogenesis Bicellular Tight Junction Assembly Basement Membrane Assembly Protein Localization To Plasma Membrane Vascular Associated Smooth Muscle Cell Development Amylin Receptor Signaling Pathway Adrenomedullin Receptor Signaling Pathway Negative Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of Vasculogenesis
Pathways			G alpha (s) signalling events Calcitonin-like ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs			Pramlintide
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil count ( 32888494)	Pulse pressure ( 30224653)
Interacting Genes		9 interacting genes: BNIP3 F2RL1 GPR35 HTR2B OPRL1 RAMP1 RAMP2 RAMP3 VKORC1	7 interacting genes: CALCA CALCRL CIDEB IAPP LCN2 SLC31A2 VIPR1
Entrez ID		1318	10266
HPRD ID		04365	05516
Ensembl ID		ENSG00000136867	ENSG00000131477
Uniprot IDs		O15432 Q53X94	A0A024R1Z2 O60895
PDB IDs			2XVT 3AQE 3AQF 4RWF 6UUN 6V2E
Enriched GO Terms of Interacting Partners?
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