AP1S3 and AAGAB

Data Source:
BioGRID (two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid)

		AP1S3	AAGAB
Description		adaptor related protein complex 1 subunit sigma 3	alpha and gamma adaptin binding protein
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Cytosol Clathrin-coated Pit Membrane Coat Cytoplasmic Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle	Cytoplasm Cytosol Nuclear Speck
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Protein Targeting Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus	Protein Transport
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Airway wall thickness ( 25517131) Asthma ( 30929738 32296059) Asthma (childhood onset) ( 30929738) Initial alcohol sensitivity ( 30276832) Night sleep phenotypes ( 27126917) Sodium levels ( 29403010)	Allergic rhinitis ( 30013184) Asthma ( 31959851 31619474 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Bipolar disorder ( 31043756) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) FEV1 ( 30804560) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Proportion of activated microglia (midfrontal cortex) ( 30679421)
Interacting Genes		2 interacting genes: AAGAB PRKAG1	9 interacting genes: AP1G1 AP1G2 AP1S3 AP2A1 AP2A2 AP2S1 EIF3C HEATR1 UNC119
Entrez ID		130340	79719
HPRD ID		16495	07754
Ensembl ID		ENSG00000152056	ENSG00000103591
Uniprot IDs		Q96PC3	Q6PD74
PDB IDs		4HMY 6CM9 6CRI 6D83 6D84 6DFF
Enriched GO Terms of Interacting Partners?
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