XIRP2 and NEB

Data Source:
BioGRID (two hybrid, pull down)

		XIRP2	NEB
Description		xin actin binding repeat containing 2	nebulin
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GO Annotations	Cellular Component	Stress Fiber Focal Adhesion	Cytosol Actin Cytoskeleton Z Disc Extracellular Exosome
	Molecular Function	Actin Filament Binding	Protein Binding Structural Constituent Of Muscle Actin Filament Binding
	Biological Process	Heart Development Biological_process Actin Cytoskeleton Organization	Muscle Organ Development Somatic Muscle Development Muscle Filament Sliding Regulation Of Actin Filament Length Muscle Fiber Development Cardiac Muscle Thin Filament Assembly
Pathways			Striated Muscle Contraction
Drugs
Diseases			Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Nemaline myopathy
GWAS		Atopic dermatitis ( 25865352) Diabetic peripheral neuropathy in type 2 diabetes ( 31127053) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Plasma renin activity levels ( 29650764)	Asparaginase-induced acute pancreatitis in acute lymphoblastic leukemia (onset time) ( 27114598) Creatine kinase levels ( 29403010) Estimated glomerular filtration rate ( 31152163 31451708) Letter-number span reordering ( 31596458) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Rapid automised naming of letters ( 30741946) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		5 interacting genes: DYSF FLNC LRRK2 NEB NEBL	24 interacting genes: ABI1 ACO1 ACTG2 ACTN4 AKTIP APC CALM1 DES ENO3 LIMS1 MTDH MYOM2 MYPN PTPN11 STRADB TMOD1 TMOD4 TPM1 TPM2 TRIM55 TRIM63 TTN XIRP1 XIRP2
Entrez ID		129446	4703
HPRD ID		10267	01196
Ensembl ID		ENSG00000163092	ENSG00000183091
Uniprot IDs		A4UGR9	P20929 Q05C45 Q96MF8
PDB IDs		4F14	1ARK 1NEB
Enriched GO Terms of Interacting Partners?
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