XIRP2 and NEBL

Data Source:
BioGRID (two hybrid, pull down, unspecified method)

		XIRP2	NEBL
Description		xin actin binding repeat containing 2	nebulette
Image
GO Annotations	Cellular Component	Stress Fiber Focal Adhesion	Stress Fiber Z Disc I Band Extracellular Exosome
	Molecular Function	Actin Filament Binding	Protein Binding Tropomyosin Binding Cytoskeletal Protein Binding Structural Constituent Of Muscle Filamin Binding Actin Filament Binding
	Biological Process	Heart Development Biological_process Actin Cytoskeleton Organization	Muscle Fiber Development Cardiac Muscle Thin Filament Assembly
Pathways
Drugs
Diseases
GWAS		Atopic dermatitis ( 25865352) Diabetic peripheral neuropathy in type 2 diabetes ( 31127053) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Plasma renin activity levels ( 29650764)	Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Atrial fibrillation ( 28416822) Coronary artery aneurysm in Kawasaki disease ( 27171184) Heel bone mineral density ( 30598549) Liver injury in combined anti-retroviral and anti-tuberculosis drug-treated HIV with tuberculosis ( 28388302) Metabolite levels ( 23823483) Ovarian cancer ( 23535730) Photic sneeze reflex ( 27182965) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681) Plasma anti-thyroid peroxidase levels ( 29678681) Pulse pressure ( 27841878) Refractive error ( 32231278) Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) ( 30166627) Sporadic pituitary adenoma ( 26029870) Urate levels in lean individuals ( 25811787) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Waist circumference ( 28552196)
Interacting Genes		5 interacting genes: DYSF FLNC LRRK2 NEB NEBL	34 interacting genes: ACAP1 ACTB ACTN1 ACTN3 CCDC125 CCDC136 CEP70 FAM9B GMCL1 GOLGA2 GOLGA6A HOMER3 KIFC3 LZTS2 MAD1L1 MIPOL1 MYPN NUTM1 PIBF1 PIK3R3 PRKAB2 QARS1 SPAG5 TRAF1 TRAF2 TRIM27 TRIM55 TRIM63 VCL XIRP1 XIRP2 ZDHHC17 ZGPAT ZYX
Entrez ID		129446	10529
HPRD ID		10267	10403
Ensembl ID		ENSG00000163092	ENSG00000078114
Uniprot IDs		A4UGR9	O76041 Q59FZ8
PDB IDs		4F14	4F14
Enriched GO Terms of Interacting Partners?
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