FGD4 and BBLN

Data Source:
BioGRID (two hybrid)

		FGD4	BBLN
Description		FYVE, RhoGEF and PH domain containing 4	bublin coiled coil protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Golgi Apparatus Cytosol Cytoskeleton Lamellipodium Filopodium	Cellular_component
	Molecular Function	Actin Binding Guanyl-nucleotide Exchange Factor Activity Small GTPase Binding Metal Ion Binding	Molecular_function Protein Binding
	Biological Process	Cytoskeleton Organization G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Apoptotic Process Regulation Of GTPase Activity Filopodium Assembly Regulation Of Small GTPase Mediated Signal Transduction	Biological_process
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Figural/spatial cognitive ability ( 31620175) Health literacy ( 31250787) Mean platelet volume ( 32888494 27863252) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer ( 32562552)
Interacting Genes		3 interacting genes: ACTA1 BBLN CDC42	8 interacting genes: ATP6V1D ATP6V1E2 CEP290 FGD4 IKBIP INPP1 KRT20 THAP11
Entrez ID		121512	79095
HPRD ID		16891	12946
Ensembl ID		ENSG00000139132	ENSG00000171159
Uniprot IDs		B7Z493 B7Z8F9 E9PJX4 F8W1R0 Q49A55 Q96M96	Q9BUW7
PDB IDs
Enriched GO Terms of Interacting Partners?
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