FGD4

Description		FYVE, RhoGEF and PH domain containing 4
Image		No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Golgi Apparatus Cytosol Cytoskeleton Lamellipodium Filopodium
	Molecular Function	Actin Binding Guanyl-nucleotide Exchange Factor Activity Small GTPase Binding Metal Ion Binding
	Biological Process	Cytoskeleton Organization G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Apoptotic Process Regulation Of GTPase Activity Filopodium Assembly Regulation Of Small GTPase Mediated Signal Transduction
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Figural/spatial cognitive ability ( 31620175) Health literacy ( 31250787) Mean platelet volume ( 32888494 27863252) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer ( 32562552)
Interacting Genes		3 interacting genes: ACTA1 BBLN CDC42
Entrez ID		121512
HPRD ID		16891
Ensembl ID		ENSG00000139132
Uniprot IDs		B7Z493 B7Z8F9 E9PJX4 F8W1R0 Q49A55 Q96M96
PDB IDs
Enriched GO Terms of Interacting Partners?
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