TM4SF18 and CLEC2D

Data Source:
BioGRID (two hybrid)

		TM4SF18	CLEC2D
Description		transmembrane 4 L six family member 18	C-type lectin domain family 2 member D
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane
	Molecular Function	Protein Binding	Transmembrane Signaling Receptor Activity Carbohydrate Binding Natural Killer Cell Lectin-like Receptor Binding
	Biological Process		Cell Surface Receptor Signaling Pathway Regulation Of Immune Response
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS			Autoimmune thyroid disease ( 32581359) HDL cholesterol levels x short total sleep time interaction (1df test) ( 31719535) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Multiple sclerosis ( 31604244)
Interacting Genes		33 interacting genes: BNIP3 CLDN19 CLEC2D CXCL9 CYB561 CYB561A3 EFNA5 EMP3 FXYD6 GIMAP5 IER3IP1 ITGB2 LAT LHFPL5 MAL MS4A13 MS4A3 NIPAL4 NSG1 PMP22 RPRM SERP2 SLC30A2 SLC39A9 SMIM3 STRIT1 TEX264 TMEM218 TRARG1 TREX1 UBE2J1 UNC93B1 VAMP5	33 interacting genes: - ADIPOQ ATP6V0C B3GALT5 BRICD5 CD68 CLDN19 CLDN2 CLEC2A CLRN2 CXCL9 DEFB121 ENTPD8 ERMP1 FAM3C FNDC9 GPR42 IL1RL1 KLRB1 KLRC1 LEPROTL1 NKG7 PLLP PLN PLP1 RPRM SEC22A SHMT2 SYT15 TM4SF18 TMEM190 TMEM80 TSPAN4
Entrez ID		116441	29121
HPRD ID		14018	16134
Ensembl ID		ENSG00000163762	ENSG00000069493
Uniprot IDs		Q96CE8	Q9UHP7 W8JXM2
PDB IDs			4QKG 4QKH 4QKI 4QKJ 4WCO 5MGT
Enriched GO Terms of Interacting Partners?
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