TM4SF18 and FXYD6

Data Source:
BioGRID (two hybrid)

		TM4SF18	FXYD6
Description		transmembrane 4 L six family member 18	FXYD domain containing ion transport regulator 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Molecular_function Protein Binding Sodium Channel Regulator Activity Ion Channel Regulator Activity
	Biological Process		Biological_process Ion Transmembrane Transport Regulation Of Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways			Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs
Diseases
GWAS			Hippocampal volume in Alzheimer's disease dementia ( 29274321) Myopia ( 27182965)
Interacting Genes		33 interacting genes: BNIP3 CLDN19 CLEC2D CXCL9 CYB561 CYB561A3 EFNA5 EMP3 FXYD6 GIMAP5 IER3IP1 ITGB2 LAT LHFPL5 MAL MS4A13 MS4A3 NIPAL4 NSG1 PMP22 RPRM SERP2 SLC30A2 SLC39A9 SMIM3 STRIT1 TEX264 TMEM218 TRARG1 TREX1 UBE2J1 UNC93B1 VAMP5	65 interacting genes: APCDD1L APH1A AQP6 ARL13B BCAR1 C4BPA CCDC90B CD74 CERS4 CLDN7 CLEC10A CREB3 CREB3L1 DERL2 EBP ELOVL2 ELOVL4 ERGIC3 FCER1G FFAR2 FPR2 GDF9 GJA8 GPR42 HAUS2 JAGN1 KCNJ6 LHFPL2 LHFPL5 LMNA MFF MGST3 MMGT1 OCIAD1 PEX12 PGRMC2 PPP1CC RBM48 RHBDL1 RHCG RNASEK SLC10A1 SLC10A6 SLC16A7 SLC30A2 SLC35C2 SLC35E1 SLC35E3 SLC39A2 SLC47A1 SVOP TLCD4 TLE1 TM4SF18 TMEM154 TMEM237 TMEM239 TMEM31 TMEM35A TMEM72 TMEM86B TMPPE TP53 TRIM27 UNC119
Entrez ID		116441	53826
HPRD ID		14018	09456
Ensembl ID		ENSG00000163762	ENSG00000137726
Uniprot IDs		Q96CE8	A0A024R3J8 Q9H0Q3
PDB IDs
Enriched GO Terms of Interacting Partners?
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