PTPMT1 and KRTAP1-3

Data Source:
BioGRID (two hybrid)

		PTPMT1	KRTAP1-3
Description		protein tyrosine phosphatase mitochondrial 1	keratin associated protein 1-3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane	Cytosol Keratin Filament
	Molecular Function	Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatidylglycerophosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Structural Constituent Of Skin Epidermis
	Biological Process	Cardiolipin Biosynthetic Process Peptidyl-tyrosine Dephosphorylation Regulation Of Intrinsic Apoptotic Signaling Pathway	Biological_process Keratinization
Pathways		Synthesis of PG	Keratinization
Drugs
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Bipolar disorder ( 31043756) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Estimated glomerular filtration rate ( 30604766) Fruit consumption ( 32066663) Glomerular filtration rate ( 29403010) Hypertension ( 27618448) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Mean arterial pressure ( 27618448) Mood instability ( 31168069) Neuroticism ( 29255261) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271)
Interacting Genes		31 interacting genes: ADAMTSL4 CYSRT1 GRN KRT31 KRT34 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-4 KRTAP3-1 KRTAP4-12 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 LCE2C MAPK6 MDFI MTUS2 NBPF19 NOTCH2NLA RGS20 SIAH1 SSC4D TAB1 TMEM14B TRIM27	176 interacting genes: ADAM12 AGA ALDH3B1 ALPP ATG9A BCAM BHLHE40 BMP7 BTC C19orf25 C2orf68 CATSPER1 CELF5 CHIC2 CHRD CHRNG CLDN2 CMTM8 CNNM3 COA5 COL8A1 CRCT1 CREB5 CRH CRY2 CTNNBIP1 CXCL16 CYHR1 CYP21A2 CYSRT1 DHRS1 DLGAP3 DMRT3 DOCK2 ECE1 FBXW5 GLP1R GLRX3 GNE GRAP2 GSTP1 HCK HHEX HHIPL1 HOXA1 HOXB9 HOXC8 HPCAL1 HSD3B7 IGSF8 IL10 IL16 INPP5D INS ITGB4 ITGB5 JOSD1 KLHL38 KPRP KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LONRF1 LRFN4 MAPKBP1 MOS MTNR1A MXD3 MXI1 MYPOP NAXD NECTIN2 NECTIN3 NID2 NMU NPBWR2 NPDC1 NR1D2 NUFIP2 OLFM2 OTX1 P3H3 PDE9A PDIA5 PHETA1 PHLDA1 PIGS PLEKHN1 PRKAA2 PRKAB2 PRPF31 PSMA1 PTK7 PTPMT1 PVR R3HDM2 RAMAC RANBP3 RASD1 RPN1 RPS19BP1 SAPCD2 SDC3 SDCBP SELENOM SHFL SLC13A5 SLC22A23 SLC23A1 SLC39A7 SLC43A2 SLC7A11 SMCP SPINT1 SPRY1 STK16 SUSD6 TACSTD2 TCAF1 TFAP2D TGFB1 THAP7 TNS2 UNC119 UTP23 UXT VASN VSTM4 WNT11 XCL2 YIPF3 YY1 ZDHHC1 ZNF330 ZNF414 ZNF417 ZNF440 ZNF446 ZNF497 ZNF587 ZNF696 ZNF764 ZNF786 ZNF837
Entrez ID		114971	81850
HPRD ID		15151	12305
Ensembl ID		ENSG00000110536	ENSG00000221880
Uniprot IDs		Q8WUK0	Q8IUG1
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?