PTPMT1 and KRTAP9-3

Data Source:
BioGRID (two hybrid)

		PTPMT1	KRTAP9-3
Description		protein tyrosine phosphatase mitochondrial 1	keratin associated protein 9-3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane	Cytosol Keratin Filament
	Molecular Function	Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatidylglycerophosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Protein Binding Identical Protein Binding
	Biological Process	Cardiolipin Biosynthetic Process Peptidyl-tyrosine Dephosphorylation Regulation Of Intrinsic Apoptotic Signaling Pathway	Keratinization
Pathways		Synthesis of PG	Keratinization
Drugs
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Bipolar disorder ( 31043756) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Estimated glomerular filtration rate ( 30604766) Fruit consumption ( 32066663) Glomerular filtration rate ( 29403010) Hypertension ( 27618448) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Mean arterial pressure ( 27618448) Mood instability ( 31168069) Neuroticism ( 29255261) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271)
Interacting Genes		31 interacting genes: ADAMTSL4 CYSRT1 GRN KRT31 KRT34 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-4 KRTAP3-1 KRTAP4-12 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 LCE2C MAPK6 MDFI MTUS2 NBPF19 NOTCH2NLA RGS20 SIAH1 SSC4D TAB1 TMEM14B TRIM27	127 interacting genes: ADAMTSL4 ANKS1A ATN1 C9orf24 CARD10 CATSPER1 CCER1 CELF5 CERCAM CHRD CHRNG CNNM3 COL8A1 CRCT1 CREB5 CRH CYSRT1 DCDC2 DMRT3 DOCK2 ECM1 FAM124B FBXO34 FBXW5 GET4 GLRX3 GNE HOXA1 HOXA9 INCA1 ITGB4 JOSD1 KLHL38 KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP13-1 KRTAP13-3 KRTAP19-2 KRTAP19-6 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LMNTD2 LNX1 MAPKBP1 MEOX2 NBPF19 NECTIN3 NOTCH2NLA NPDC1 NR1D2 NR4A3 NTM NUFIP2 OTX1 PAX5 PAX6 PHLDA1 POU4F2 PRKAB2 PTPMT1 PVR RAMP3 RGS20 SH3GLB2 SHFL SLC13A5 SLC23A1 SLC25A18 SMCP SPRY1 TFAP2D TOX3 TRIM42 TSPAN4 UNC119 VASN VGLL3 WNT11 YY1 ZNF414 ZNF439 ZNF440 ZNF497 ZNF575
Entrez ID		114971	83900
HPRD ID		15151	13950
Ensembl ID		ENSG00000110536	ENSG00000204873
Uniprot IDs		Q8WUK0	Q9BYQ3
PDB IDs
Enriched GO Terms of Interacting Partners?
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