MGLL and MFSD14B

Data Source:
BioGRID (two hybrid)

		MGLL	MFSD14B
Description		monoglyceride lipase	major facilitator superfamily domain containing 14B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Extrinsic Component Of Membrane	Integral Component Of Membrane
	Molecular Function	Lysophospholipase Activity Protein Binding Lipase Activity Protein Homodimerization Activity Acylglycerol Lipase Activity	Protein Binding Transmembrane Transporter Activity
	Biological Process	Lipid Metabolic Process Fatty Acid Biosynthetic Process Inflammatory Response Regulation Of Signal Transduction Arachidonic Acid Metabolic Process Triglyceride Catabolic Process Acylglycerol Acyl-chain Remodeling Acylglycerol Catabolic Process Regulation Of Inflammatory Response Regulation Of Sensory Perception Of Pain Monoacylglycerol Catabolic Process Regulation Of Endocannabinoid Signaling Pathway	Transmembrane Transport
Pathways		Acyl chain remodeling of DAG and TAG Triglyceride catabolism Arachidonate production from DAG
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Carotid intima media thickness x smoking interaction ( 32117412) Pars triangularis volume ( 31530798) Refractive error ( 32231278)
Interacting Genes		25 interacting genes: ADRB2 AQP6 CD79A CHGB COQ9 EBAG9 FAM209A FCER1G GEM GOLT1A GPR152 HSD17B13 HTR4 LMNA LTB4R2 MFSD14B MSRB3 PEX12 SDCBP SLC10A6 SLC66A2 SLC7A14 STOM TMEM35A TMX2	75 interacting genes: ADIPOQ AGPAT3 AGPAT4 ARL6IP1 ATP13A1 BNIP3 C14orf180 C4orf3 CCL4L2 CFHR5 CLDN4 CMTM3 COMT CSGALNACT2 CTSA CYB5B CYBC1 DEFB127 DNAJC30 EMC6 ERG28 FKBP8 FMO1 FUNDC2 GIMAP1 GOSR2 GRM2 KTN1 LAT LEPROTL1 LPCAT2 LRP10 MGLL MS4A1 NAT8 ORMDL1 PEX16 PKMYT1 PRRT2 RNF24 SACM1L SCD SERP1 SERP2 SLC25A46 SLC39A9 SLC66A2 SMAGP STX3 TECR THSD7B TIMMDC1 TMBIM6 TMEM119 TMEM167B TMEM176A TMEM19 TMEM208 TMEM229B TMEM239 TMEM31 TMX2 TPRG1 TRARG1 TREX1 TSNARE1 UBE2J1 UNC50 USE1 YIPF1 YIPF2 YIPF4 YIPF6 ZDHHC24 ZFPL1
Entrez ID		11343	84641
HPRD ID		17574	07869
Ensembl ID		ENSG00000074416	ENSG00000148110
Uniprot IDs		A0A0C4DFN3 B2ZGL7 E7EWX8 Q99685	Q5SR56
PDB IDs		3HJU 3JW8 3JWE 3PE6 4UUQ 5ZUN 6AX1 6BQ0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
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