MGLL and LTB4R2

Data Source:
BioGRID (two hybrid)

		MGLL	LTB4R2
Description		monoglyceride lipase	leukotriene B4 receptor 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Extrinsic Component Of Membrane	Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Lysophospholipase Activity Protein Binding Lipase Activity Protein Homodimerization Activity Acylglycerol Lipase Activity	Leukotriene B4 Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process	Lipid Metabolic Process Fatty Acid Biosynthetic Process Inflammatory Response Regulation Of Signal Transduction Arachidonic Acid Metabolic Process Triglyceride Catabolic Process Acylglycerol Acyl-chain Remodeling Acylglycerol Catabolic Process Regulation Of Inflammatory Response Regulation Of Sensory Perception Of Pain Monoacylglycerol Catabolic Process Regulation Of Endocannabinoid Signaling Pathway	Chemotaxis Inflammatory Response G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Neuropeptide Signaling Pathway Leukotriene Signaling Pathway
Pathways		Acyl chain remodeling of DAG and TAG Triglyceride catabolism Arachidonate production from DAG	Leukotriene receptors G alpha (q) signalling events
Drugs			Amelubant Leukotriene B4
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Carotid intima media thickness x smoking interaction ( 32117412) Pars triangularis volume ( 31530798) Refractive error ( 32231278)	Anorectal malformation ( 31136621) Height ( 28552196)
Interacting Genes		25 interacting genes: ADRB2 AQP6 CD79A CHGB COQ9 EBAG9 FAM209A FCER1G GEM GOLT1A GPR152 HSD17B13 HTR4 LMNA LTB4R2 MFSD14B MSRB3 PEX12 SDCBP SLC10A6 SLC66A2 SLC7A14 STOM TMEM35A TMX2	46 interacting genes: AKT1 AP2M1 CANX CEBPZ CERS1 CHPT1 CNOT10 CRELD2 CSNK2B CTSA DDOST FOLR1 GJC2 GLOD4 GPR146 GPR37 HLA-A IL17RD IMP4 LAMP5 MDH1 MGLL MYO1E OBSL1 P4HTM PER1 PIGM PKD1 RPN2 SCARB1 SEC13 SGCB SLC2A1 STMN3 SV2A SYNGR2 TMED1 TMEM94 TMUB2 TSPAN3 TSPAN4 TSPAN7 TTC9B VPS25 WFS1 YIF1B
Entrez ID		11343	56413
HPRD ID		17574	16153
Ensembl ID		ENSG00000074416	ENSG00000213906
Uniprot IDs		A0A0C4DFN3 B2ZGL7 E7EWX8 Q99685	B4E292 Q9NPC1
PDB IDs		3HJU 3JW8 3JWE 3PE6 4UUQ 5ZUN 6AX1 6BQ0
Enriched GO Terms of Interacting Partners?
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