SNF8 and RILP

Data Source:
BioGRID (pull down)

		SNF8	RILP
Description		SNF8 subunit of ESCRT-II	Rab interacting lysosomal protein
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GO Annotations	Cellular Component	ESCRT II Complex Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol Plasma Membrane Endosome Membrane Membrane Late Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome	Cytoplasm Lysosome Lysosomal Membrane Late Endosome Cytosol Phagocytic Vesicle Membrane Late Endosome Membrane Protein-containing Complex Ciliary Basal Body
	Molecular Function	Protein Binding Protein C-terminus Binding Transcription Factor Binding Channel Regulator Activity Protein Homodimerization Activity Protein N-terminus Binding	Protein Binding Small GTPase Binding Protein Dimerization Activity Dynein Light Intermediate Chain Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Regulation Of Multivesicular Body Size Involved In Endosome Transport Endosomal Transport Macroautophagy Endocytic Recycling Multivesicular Body Assembly Regulation Of Protein Catabolic Process Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of MAP Kinase Activity Early Endosome To Late Endosome Transport Positive Regulation Of Protein Catabolic Process Regulation Of Protein Complex Stability Multivesicular Body Sorting Pathway Positive Regulation Of Exosomal Secretion Regulation Of Viral Budding Via Host ESCRT Complex	Endosome To Lysosome Transport Regulation Of Multivesicular Body Size Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Protein Catabolic Process Early Endosome To Late Endosome Transport Positive Regulation Of Protein Catabolic Process Cilium Assembly Intralumenal Vesicle Formation
Pathways		Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events	MHC class II antigen presentation
Drugs
Diseases
GWAS		Coronary heart disease ( 21378990) Type 2 diabetes ( 29358691)
Interacting Genes		24 interacting genes: ADORA1 AKAP9 CHMP6 CLP1 CT55 DVL2 ELL FANCL GLYCTK GOLGA2 KDM1A NIF3L1 PRMT6 RILP SMARCD1 SUOX SUV39H2 TRIM54 TSG101 TXLNA VAC14 VPS25 VPS36 YWHAE	12 interacting genes: KPNA2 LDB2 RAB34 RAB7A RCHY1 SNF8 VPS11 VPS16 VPS18 VPS36 VPS39 VPS41
Entrez ID		11267	83547
HPRD ID		16847	09706
Ensembl ID		ENSG00000159210	ENSG00000167705
Uniprot IDs		Q96H20	Q96NA2
PDB IDs		2ZME 3CUQ	1YHN
Enriched GO Terms of Interacting Partners?
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