RAPGEF4 and ZC3H11A

Data Source:
BioGRID (two hybrid)

		RAPGEF4	ZC3H11A
Description		Rap guanine nucleotide exchange factor 4	zinc finger CCCH-type containing 11A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane Hippocampal Mossy Fiber To CA3 Synapse	Transcription Export Complex Nucleoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding CAMP Binding Small GTPase Binding	RNA Binding MRNA Binding Protein Binding Metal Ion Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Calcium-ion Regulated Exocytosis Regulation Of Exocytosis CAMP-mediated Signaling Insulin Secretion Regulation Of Catalytic Activity Regulation Of Insulin Secretion Regulation Of Synaptic Vesicle Cycle	RNA Export From Nucleus MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus MRNA 3'-end Processing
Pathways		Integrin signaling Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Rap1 signalling Regulation of insulin secretion	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Fasting plasma glucose ( 25187374) GLP-1 levels in response to oral glucose tolerance test (fasting) ( 29093273) HDL cholesterol levels ( 32203549) Hippocampal volume ( 25625606) Lateral ventricle temporal horn volume ( 31530798)	Breast cancer ( 25038754) Male-pattern baldness ( 28196072)
Interacting Genes		13 interacting genes: ATXN1 BMERB1 DEF6 LRRK2 MAP1A RAP1A RAP2A RIMS2 RRAS2 SWAP70 TRAF2 TSPOAP1 ZC3H11A	9 interacting genes: MIR141 MIR214 MIR9-1 MIR9-2 MLH1 MTNR1A RAPGEF4 SMARCB1 SUMO2
Entrez ID		11069	9877
HPRD ID		06929	11100
Ensembl ID		ENSG00000091428	ENSG00000058673
Uniprot IDs		B7Z278 Q8WZA2	O75152
PDB IDs
Enriched GO Terms of Interacting Partners?
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