ERP29 and BMP10

Data Source:
BioGRID (two hybrid)

		ERP29	BMP10
Description		endoplasmic reticulum protein 29	bone morphogenetic protein 10
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Smooth Endoplasmic Reticulum Cell Surface Membrane Transport Vesicle Melanosome	Extracellular Region Extracellular Space Cytoplasm Cell Surface Z Disc
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding Protein Homodimerization Activity Chaperone Binding	Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Telethonin Binding Receptor Serine/threonine Kinase Binding
	Biological Process	Activation Of MAPK Activity Positive Regulation Of Protein Phosphorylation Protein Folding Intracellular Protein Transport Protein Secretion Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Protein Phosphopantetheinylation Protein Unfolding Negative Regulation Of Protein Secretion Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Kidney Development Cell Adhesion Adult Heart Development Negative Regulation Of Endothelial Cell Migration Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cell Growth Negative Regulation Of Cell Migration BMP Signaling Pathway Activin Receptor Signaling Pathway Sarcomere Organization Positive Regulation Of Transcription, DNA-templated Atrial Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Cell Development Regulation Of Cardiac Muscle Contraction Cardiac Muscle Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Sarcomere Organization Heart Trabecula Formation Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction Positive Regulation Of Cartilage Development Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Pathways			Signaling by BMP Molecules associated with elastic fibres
Drugs
Diseases
GWAS		Body mass index ( 26426971) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)
Interacting Genes		18 interacting genes: ADIPOQ BMP10 C3orf52 DESI1 GLP1R HMG20B HSPA5 NRM SGTA SGTB SLC35B4 SLC38A7 TMBIM6 TMEM86B TSPO2 UBQLN1 UBQLN2 UBQLN4	59 interacting genes: ACVR2A ACVR2B APOA5 AQP6 ARL13B BIK BMPR2 BSCL2 BSND CCDC70 CD33 CISD2 CLDN7 COQ9 CREB3L1 DEXI EBP ERP29 FAM209A FCGR1A FCRL4 FFAR2 FKBP7 FNDC9 GGT6 GJB1 GPR152 GPX8 IL3RA JAGN1 KIR2DL3 KIR3DL1 KLRC1 LRRC25 LRRC4C MGST3 MRPS18B MS4A3 MTIF3 PLPP4 REEP4 SERINC3 SIT1 SLC10A1 SLC10A6 SLC35C2 SLC38A1 SLC4A1 SPAG4 TCTA TMEM14B TMEM31 TMEM45B TMEM86B TMPRSS2 TNFSF14 TNFSF8 TSPAN31 VSIR
Entrez ID		10961	27302
HPRD ID		03794	09788
Ensembl ID		ENSG00000089248	ENSG00000163217
Uniprot IDs		F8VY02 P30040 V9HW71	O95393
PDB IDs		2QC7 5V8Z 5V90	6SF1 6SF3
Enriched GO Terms of Interacting Partners?
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