RALBP1 and REPS2

Data Source:
HPRD (in vitro, two hybrid)

		RALBP1	REPS2
Description		ralA binding protein 1	RALBP1 associated Eps domain containing 2
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GO Annotations	Cellular Component	Cytosol Membrane	Cytoplasm Cytosol Plasma Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Transmembrane Transporter Activity Small GTPase Binding ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity	Calcium Ion Binding Protein Binding
	Biological Process	Endocytosis Chemotaxis Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Doxorubicin Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane	Endocytosis Epidermal Growth Factor Receptor Signaling Pathway Endosomal Transport Membrane Organization Protein-containing Complex Assembly
Pathways		Rho GTPase cycle	Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		LDL cholesterol ( 30275531)
Interacting Genes		44 interacting genes: AMOTL2 AP2M1 C1orf216 CASP8 CBY1 CCDC13 CCDC136 CCDC88B CCHCR1 CCNB1 CEP57 CREBZF FADD GAS8 GSE1 HOOK2 HSF1 IKBKG KANK2 LDOC1 MSANTD4 PCM1 PLCG2 PPP1R13B PRKCA RAC1 RALA RALB REPS1 REPS2 RHOU SAPCD2 SMARCE1 SYCE1 SYNJ2BP TBRG1 TCP10L TFPT TNIP1 TP53BP2 TRAF2 TSFM ZBTB38 ZNF707	13 interacting genes: AR ASAP1 ASAP2 CDK1 CDK5RAP2 EPN1 EPS15 GRB2 PXN RALB RALBP1 RELA REPS1
Entrez ID		10928	9185
HPRD ID		09013	02262
Ensembl ID		ENSG00000017797	ENSG00000169891
Uniprot IDs		Q15311	Q8NFH8
PDB IDs		2KWH 2KWI 2MBG	1IQ3
Enriched GO Terms of Interacting Partners?
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