RALBP1 and PCM1

Data Source:
BioGRID (two hybrid)

		RALBP1	PCM1
Description		ralA binding protein 1	pericentriolar material 1
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GO Annotations	Cellular Component	Cytosol Membrane	Pericentriolar Material Cytoplasm Centrosome Centriole Cytosol Membrane Nuclear Membrane Protein-containing Complex Centriolar Satellite Ciliary Transition Zone Ciliary Basal Body Apical Part Of Cell Non-motile Cilium
	Molecular Function	GTPase Activator Activity Protein Binding Transmembrane Transporter Activity Small GTPase Binding ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity	Protein Binding Identical Protein Binding
	Biological Process	Endocytosis Chemotaxis Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Doxorubicin Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane	G2/M Transition Of Mitotic Cell Cycle Neuron Migration Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Interkinetic Nuclear Migration Cytoplasmic Microtubule Organization Microtubule Anchoring Microtubule Anchoring At Centrosome Social Behavior Intraciliary Transport Involved In Cilium Assembly Negative Regulation Of Neurogenesis Cilium Assembly Protein Localization To Centrosome Positive Regulation Of Intracellular Protein Transport Neuronal Stem Cell Population Maintenance Ciliary Basal Body-plasma Membrane Docking Non-motile Cilium Assembly
Pathways		Rho GTPase cycle	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		LDL cholesterol ( 30275531)	Atrial fibrillation ( 28416818) Economic and political preferences ( 22566634) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Triglyceride levels ( 32203549) Waist-hip ratio ( 30108283) Weight ( 28552196)
Interacting Genes		44 interacting genes: AMOTL2 AP2M1 C1orf216 CASP8 CBY1 CCDC13 CCDC136 CCDC88B CCHCR1 CCNB1 CEP57 CREBZF FADD GAS8 GSE1 HOOK2 HSF1 IKBKG KANK2 LDOC1 MSANTD4 PCM1 PLCG2 PPP1R13B PRKCA RAC1 RALA RALB REPS1 REPS2 RHOU SAPCD2 SMARCE1 SYCE1 SYNJ2BP TBRG1 TCP10L TFPT TNIP1 TP53BP2 TRAF2 TSFM ZBTB38 ZNF707	43 interacting genes: ABI1 ABI2 AKAP9 BBS4 CASK CCDC172 CCHCR1 CDC42 CEP72 CYTH4 DDIT3 DDX23 DYNLL1 E2F4 ECPAS EPS8 EXOC8 FAM81A FXR2 GABARAP GOLGA2 HAP1 ING5 KLC1 KLC4 KRT15 KRT19 KRT24 MCRS1 NDC80 NECAB2 PCNT PRC1 PRKCI RALBP1 RBM5 RINT1 RPA2 TFIP11 TTC8 WASHC3 YWHAE YWHAQ
Entrez ID		10928	5108
HPRD ID		09013	02624
Ensembl ID		ENSG00000017797	ENSG00000078674
Uniprot IDs		Q15311	A2RUU9 B9EIS5 Q15154
PDB IDs		2KWH 2KWI 2MBG	6HYL 6HYM
Enriched GO Terms of Interacting Partners?
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