UTP14A and PTPRS

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UTP14A	PTPRS
Description		UTP14A small subunit processome component	protein tyrosine phosphatase receptor type S
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytosol Small-subunit Processome	Cytosol Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Synaptic Vesicle Membrane Axon Growth Cone Perikaryon Extracellular Exosome Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Integral Component Of Presynaptic Membrane Integral Component Of Postsynaptic Density Membrane
	Molecular Function	RNA Binding Protein Binding	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Heparin Binding Chondroitin Sulfate Binding Heparan Sulfate Proteoglycan Binding
	Biological Process	RRNA Processing	Protein Dephosphorylation Negative Regulation Of Neuron Projection Development Spinal Cord Development Cerebellum Development Hippocampus Development Cerebral Cortex Development Corpus Callosum Development Negative Regulation Of Axon Extension Negative Regulation Of Interferon-alpha Production Negative Regulation Of Interferon-beta Production Negative Regulation Of Toll-like Receptor 9 Signaling Pathway Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Modulation Of Chemical Synaptic Transmission Negative Regulation Of Dendritic Spine Development Establishment Of Endothelial Intestinal Barrier Regulation Of Postsynaptic Density Assembly Synaptic Membrane Adhesion
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	ECM proteoglycans Receptor-type tyrosine-protein phosphatases Synaptic adhesion-like molecules Signaling by NTRK3 (TRKC)
Drugs			Alendronic acid Etidronic acid
Diseases
GWAS			Thyroid stimulating hormone levels ( 32769997) Type 2 diabetes ( 30297969) Waist-hip ratio ( 28552196)
Interacting Genes		46 interacting genes: AKTIP APLP1 APP ARIH2 AXIN1 CCDC106 CCDC85B CEP70 CPE CSNK2A1 CSNK2B DLEU1 GADD45G HNRNPH3 HOOK2 HTT LAMTOR5 LDOC1 LMO1 LSM3 NINL PDCD5 PDZK1IP1 PHF10 PRKCZ PSG1 PTEN PTPRS RABIF RGS1 RHOH RNF10 RPA2 RSRC1 SAT1 SMYD1 SSR1 TERF1 TINAGL1 TP53 TP53BP2 TRDMT1 TXLNB VIM WDR33 ZNF24	27 interacting genes: CEP126 CHD3 EEF1G EGFR FEZ1 GPC2 GPC3 GPC6 KAT5 MOB4 PFN2 PPFIA1 PPFIA2 PPFIA3 PTN PTPRA PTPRD PTPRE PTPRM PTPRN RAB35 SETDB1 SLITRK1 TUBB2A UBR1 UNC119 UTP14A
Entrez ID		10813	5802
HPRD ID		06712	03344
Ensembl ID		ENSG00000156697	ENSG00000105426
Uniprot IDs		Q9BVJ6	Q13332 Q59FX6 Q8NHS7
PDB IDs			2FH7 2YD2 2YD3 2YD9 4BPC 4PBX
Enriched GO Terms of Interacting Partners?
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