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AGR2 and USP20
Data Source:
BioGRID
(two hybrid)
AGR2
USP20
Description
anterior gradient 2, protein disulphide isomerase family member
ubiquitin specific peptidase 20
Image
GO Annotations
Cellular Component
Extracellular Space
Endoplasmic Reticulum
Cytoplasm
Centrosome
Cytosol
Perinuclear Region Of Cytoplasm
Molecular Function
Dystroglycan Binding
Epidermal Growth Factor Receptor Binding
Protein Binding
Identical Protein Binding
G Protein-coupled Receptor Binding
Cysteine-type Endopeptidase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Zinc Ion Binding
Biological Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cell-substrate Adhesion
Response To Endoplasmic Reticulum Stress
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Digestive Tract Morphogenesis
Positive Regulation Of Developmental Growth
Negative Regulation Of Cell Death
Mucus Secretion
Positive Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of IRE1-mediated Unfolded Protein Response
Positive Regulation Of PERK-mediated Unfolded Protein Response
Ubiquitin-dependent Protein Catabolic Process
Endocytosis
Regulation Of G Protein-coupled Receptor Signaling Pathway
Protein Deubiquitination
Protein Phosphopantetheinylation
Protein K63-linked Deubiquitination
Protein K48-linked Deubiquitination
Pathways
Ub-specific processing proteases
Drugs
Diseases
GWAS
Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) (
23648065
)
Iron status biomarkers (ferritin levels) (
28334935
)
Residual cognition (
28441426
)
Type 2 diabetes (dietary heme iron intake interaction) (
23386860
)
Metabolite levels (
23823483
)
Interacting Genes
87 interacting genes:
ANKRD11
APOBEC3B
APP
ASPH
BORCS8
BORCS8-MEF2B
BRD7
C3
CAMLG
CATSPER1
CCDC90B
CD34
CD68
CDKN2AIPNL
CETN3
CKAP2
CLIC3
CNNM3
CPNE6
CRCP
CREB1
CRMP1
CRYGA
CYB5R2
DAG1
DCAF11
EIF3F
FABP2
FAM110A
FAM117B
GET3
GPSM2
GRB2
GUCA1A
HCK
HMG20A
HSD3B7
IL36RN
IMPDH2
KLHL38
KRT31
LSM1
LYPD3
MBD3
MBLAC1
MED31
MLH1
NDUFB2
NRF1
NRIP1
NSD1
NTAQ1
NUP54
NUP58
NUP62CL
OSTF1
PHC3
POGZ
POLR2L
POM121
PSMA1
PSMB1
PSORS1C2
PTTG2
RBFOX1
RBP5
RIIAD1
RTL4
RUVBL2
SDC3
SGTA
SGTB
SH2D1B
STK16
TCEA2
TFAP2D
THOC1
TLE5
TMEM123
TRAF2
TSTD2
UBE2I
UBQLN1
UBQLN2
UBQLN4
USP20
VEZF1
69 interacting genes:
AGR2
ALAS1
APBA2
ARID5A
ASCL1
ATP6V1G2
BEND5
BEND7
BHLHB9
BRPF1
C1QTNF2
CCNL2
CDK2AP1
CLSPN
CTAG1A
CTAG1B
DIO2
ENKD1
EPAS1
FATE1
FTO
GPRASP2
GTF2IRD1
HAND2
HIF1A
HSF2BP
IHO1
IRAK1BP1
ITGB3BP
KLHL20
LMNA
MAGEA11
MAPK6
MBD3L1
MCCD1
MDFI
MEOX2
MRPL28
PBX4
PJA1
PLA2G2A
PRKACA
PRKCI
RAD17
RSPO4
SAMD12
SPRY2
SRGAP2B
STING1
TNNI1
TRIB3
TRIM23
TTC19
TTC23L
ULK1
USP15
USP21
USP28
VAPA
VAPB
VAX1
VHL
WASHC1
ZBTB10
ZFYVE26
ZNF343
ZNF408
ZNF620
ZXDB
Entrez ID
10551
10868
HPRD ID
05896
07505
Ensembl ID
ENSG00000106541
ENSG00000136878
Uniprot IDs
O95994
Q4JM46
Q9Y2K6
PDB IDs
2LNS
2LNT
6KCZ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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