USP20 and MRPL28

Data Source:
BioGRID (two hybrid)

		USP20	MRPL28
Description		ubiquitin specific peptidase 20	mitochondrial ribosomal protein L28
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GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Perinuclear Region Of Cytoplasm	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit Cytosol
	Molecular Function	G Protein-coupled Receptor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Endocytosis Regulation Of G Protein-coupled Receptor Signaling Pathway Protein Deubiquitination Protein Phosphopantetheinylation Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination	Translation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		Ub-specific processing proteases	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Body mass index ( 26426971) Heel bone mineral density ( 28869591) Refractive error ( 32231278)
Interacting Genes		69 interacting genes: AGR2 ALAS1 APBA2 ARID5A ASCL1 ATP6V1G2 BEND5 BEND7 BHLHB9 BRPF1 C1QTNF2 CCNL2 CDK2AP1 CLSPN CTAG1A CTAG1B DIO2 ENKD1 EPAS1 FATE1 FTO GPRASP2 GTF2IRD1 HAND2 HIF1A HSF2BP IHO1 IRAK1BP1 ITGB3BP KLHL20 LMNA MAGEA11 MAPK6 MBD3L1 MCCD1 MDFI MEOX2 MRPL28 PBX4 PJA1 PLA2G2A PRKACA PRKCI RAD17 RSPO4 SAMD12 SPRY2 SRGAP2B STING1 TNNI1 TRIB3 TRIM23 TTC19 TTC23L ULK1 USP15 USP21 USP28 VAPA VAPB VAX1 VHL WASHC1 ZBTB10 ZFYVE26 ZNF343 ZNF408 ZNF620 ZXDB	28 interacting genes: ABI2 APP BANP CDCA7L CDR2 ENKD1 FAM9B HMBOX1 HSPB1 HTR2A IKZF3 LARP1B LENG1 LRRK2 NFKBID OXA1L PPL SCNM1 TEF TRAF3IP2 TRAF4 TSHZ3 TSSK3 TUBB3 UPP2 USP2 USP20 ZNF655
Entrez ID		10868	10573
HPRD ID		07505	06889
Ensembl ID		ENSG00000136878	ENSG00000086504
Uniprot IDs		Q9Y2K6	Q13084
PDB IDs		6KCZ	3J7Y 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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