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DCTN2 and BICD1
Data Source:
HPRD
(in vivo)
DCTN2
BICD1
Description
dynactin subunit 2
BICD cargo adaptor 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Kinetochore
Cytoplasm
Centrosome
Cytosol
Dynactin Complex
Microtubule
Membrane
Dynein Complex
Growth Cone
Vesicle
Extracellular Exosome
Golgi Apparatus
Trans-Golgi Network
Centrosome
Cytosol
Cytoskeleton
Cytoplasmic Microtubule
Membrane
Cytoplasmic Vesicle
Tubulin Complex
Perinuclear Region Of Cytoplasm
Secretory Vesicle
Molecular Function
Motor Activity
Protein Binding
Protein Kinase Binding
Spectrin Binding
Identical Protein Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Cytoskeletal Anchor Activity
Protein Kinase Binding
Small GTPase Binding
Proteinase Activated Receptor Binding
Dynactin Binding
Dynein Intermediate Chain Binding
Dynein Complex Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Mitotic Spindle Organization
Mitotic Metaphase Plate Congression
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Melanosome Transport
Protein Localization To Centrosome
Ciliary Basal Body-plasma Membrane Docking
RNA Processing
Intracellular MRNA Localization
Anatomical Structure Morphogenesis
Viral Process
Protein Localization To Organelle
Stress Granule Assembly
Positive Regulation Of Receptor-mediated Endocytosis
Regulation Of Microtubule Cytoskeleton Organization
Minus-end-directed Organelle Transport Along Microtubule
Microtubule Anchoring At Microtubule Organizing Center
Negative Regulation Of Phospholipase C Activity
Regulation Of Proteinase Activated Receptor Activity
Negative Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Protein Localization To Centrosome
Pathways
MHC class II antigen presentation
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
COPI-mediated anterograde transport
COPI-independent Golgi-to-ER retrograde traffic
AURKA Activation by TPX2
COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Emphysema-related traits (
20709820
)
Fourth ventricle volume (
31530798
)
Left ventricular mass x antihypertensive treatment interaction (
31407531
)
Normalized brain volume (
19010793
)
Obesity-related traits (
23251661
)
Pancreatic cancer (
20686608
)
Parkinson's disease (
32201043
)
Interacting Genes
35 interacting genes:
ABI2
BICD1
BICD2
BLOC1S1
BLOC1S2
BLOC1S6
BORCS6
CALM1
CCDC172
CENPH
CEP44
COG3
DISC1
EGFR
GADD45A
GADD45G
GNAO1
GOLM1
GRB2
GSK3B
HAUS1
HGS
KIFC3
KPNA2
MAPK6
MAPRE3
MARCKSL1
PAFAH1B1
RABGEF1
RINT1
RPGR
SMARCD1
TXLNB
USHBP1
ZW10
12 interacting genes:
ALPI
CPNE4
DCTN1
DCTN2
DISC1
DYNC1I1
GSK3A
GSK3B
MAPK14
NIN
RAB6A
STAT3
Entrez ID
10540
636
HPRD ID
09568
03730
Ensembl ID
ENSG00000175203
ENSG00000151746
Uniprot IDs
A0A384MDU9
A8K8J9
B3KTX4
Q13561
V9HW58
Q96G01
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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