MCRS1 and PSTPIP1

Data Source:
BioGRID (two hybrid)

		MCRS1	PSTPIP1
Description		microspherule protein 1	proline-serine-threonine phosphatase interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Polysome Dendrite Ino80 Complex Perikaryon NSL Complex MLL1 Complex	Uropod Cytoplasm Cytosol Cytoskeleton Actin Filament Plasma Membrane Membrane Lamellipodium Cleavage Furrow Perinuclear Region Of Cytoplasm
	Molecular Function	G-quadruplex RNA Binding Protein Binding Poly(U) RNA Binding Poly(G) Binding	Protein Binding Identical Protein Binding Actin Filament Binding
	Biological Process	DNA Repair DNA Recombination Cellular Protein Modification Process Viral Process Protein Deubiquitination Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Localization To Nucleolus	Endocytosis Inflammatory Response Cell Adhesion Signal Transduction Actin Filament Polymerization Innate Immune Response
Pathways		HATs acetylate histones UCH proteinases DNA Damage Recognition in GG-NER	The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection
Drugs
Diseases			Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome
GWAS			Neurofibrillary tangles ( 31497858) Neutrophil count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		126 interacting genes: AGGF1 AXIN2 BACH2 BEND3 BHLHA9 BHLHE40 BLM BRD8 BRMS1 BRMS1L C18orf25 C2CD6 C7orf57 C8orf34 CARD9 CAVIN2 CBY2 CCDC13 CCDC136 CCDC85B CCHCR1 CCNH CDCA7L CEP44 CEP70 CNTROB COIL CREB3L3 CSRNP1 CYSRT1 CYTIP DAXX DRAP1 DVL2 EGR2 ERF EVI5 FAM9A FNDC8 FSD2 FXR1 FXR2 GAS7 GCC1 GEM GIGYF1 GOLGA2 GPBP1 HMBOX1 HOOK2 IKZF1 IKZF3 IKZF4 INO80E INSYN1 JAKMIP1 KANK2 KAT7 KDM1A KIAA1958 KRT35 KRTAP10-7 KRTAP2-3 KRTAP2-4 KXD1 LIG4 LSM6 LZTS1 MAGEA11 MAGEA6 MAPK9 MED4 MEOX1 MFAP1 MIER2 MIER3 NAA10 NAB2 NKAPD1 NOP2 OSBPL3 PBK PBX2 PCM1 PHC2 PIBF1 PINX1 PKNOX2 PPP1R13B PRMT5 PSTPIP1 PTEN RABEP1 RALYL RARA RETREG3 RIPPLY3 SH2B2 SNAPC5 SP4 SRRM4 SSMEM1 SUV39H1 TADA2B TBC1D1 TERT TFAP4 TLE5 TNIP1 TNNI1 TP63 TRIM37 TRIM41 TSPYL2 UPF3B USHBP1 WASHC3 WBP11 XIAP ZBTB22 ZCCHC10 ZCCHC12 ZNF23 ZNF639 ZNF8 ZRANB1	64 interacting genes: ABL1 AXIN1 BUB3 CCDC172 CD2 CD2AP CHD4 CWF19L2 DHX40 DNM2 EHHADH EXOC5 FAM90A1 FASLG FBXL18 HAPLN2 HHEX HMG20A HSF2BP IL16 KANK2 KHDRBS1 LIN37 LSM4 MCRS1 MEFV MOS MVP NAV2 NCBP1 PCDHB14 PNKP PRPF31 PRR35 PTPN12 PTPN18 RINT1 RNPS1 RPL9 RTP5 RXRB SCNM1 SDCBP SH2D4A SHBG SMARCD1 SPG7 SYCE1 TFIP11 TPH1 TRAF3IP3 TSGA10IP TTC1 TULP3 UBE2W WAS WASF1 WASF2 WASL ZC2HC1C ZNF175 ZNF408 ZNF580 ZNF688
Entrez ID		10445	9051
HPRD ID		11298	05891
Ensembl ID		ENSG00000187778	ENSG00000140368
Uniprot IDs		A0A024R134 Q96EZ8	A0A0S2Z5P3 O43586
PDB IDs			2DIL
Enriched GO Terms of Interacting Partners?
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