MCRS1 and C18orf25

Data Source:
BioGRID (two hybrid)

		MCRS1	C18orf25
Description		microspherule protein 1	chromosome 18 open reading frame 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Polysome Dendrite Ino80 Complex Perikaryon NSL Complex MLL1 Complex
	Molecular Function	G-quadruplex RNA Binding Protein Binding Poly(U) RNA Binding Poly(G) Binding	Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	DNA Repair DNA Recombination Cellular Protein Modification Process Viral Process Protein Deubiquitination Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Localization To Nucleolus	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination
Pathways		HATs acetylate histones UCH proteinases DNA Damage Recognition in GG-NER
Drugs
Diseases
GWAS			Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid AB1-42 levels ( 29274321) Clinical laboratory measurements ( 27897004) Eosinophil counts ( 32888494) Granulocyte count ( 27863252) Hemoglobin ( 32888494) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 29403010 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 29403010 32888494 27863252) Mean platelet volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252)
Interacting Genes		126 interacting genes: AGGF1 AXIN2 BACH2 BEND3 BHLHA9 BHLHE40 BLM BRD8 BRMS1 BRMS1L C18orf25 C2CD6 C7orf57 C8orf34 CARD9 CAVIN2 CBY2 CCDC13 CCDC136 CCDC85B CCHCR1 CCNH CDCA7L CEP44 CEP70 CNTROB COIL CREB3L3 CSRNP1 CYSRT1 CYTIP DAXX DRAP1 DVL2 EGR2 ERF EVI5 FAM9A FNDC8 FSD2 FXR1 FXR2 GAS7 GCC1 GEM GIGYF1 GOLGA2 GPBP1 HMBOX1 HOOK2 IKZF1 IKZF3 IKZF4 INO80E INSYN1 JAKMIP1 KANK2 KAT7 KDM1A KIAA1958 KRT35 KRTAP10-7 KRTAP2-3 KRTAP2-4 KXD1 LIG4 LSM6 LZTS1 MAGEA11 MAGEA6 MAPK9 MED4 MEOX1 MFAP1 MIER2 MIER3 NAA10 NAB2 NKAPD1 NOP2 OSBPL3 PBK PBX2 PCM1 PHC2 PIBF1 PINX1 PKNOX2 PPP1R13B PRMT5 PSTPIP1 PTEN RABEP1 RALYL RARA RETREG3 RIPPLY3 SH2B2 SNAPC5 SP4 SRRM4 SSMEM1 SUV39H1 TADA2B TBC1D1 TERT TFAP4 TLE5 TNIP1 TNNI1 TP63 TRIM37 TRIM41 TSPYL2 UPF3B USHBP1 WASHC3 WBP11 XIAP ZBTB22 ZCCHC10 ZCCHC12 ZNF23 ZNF639 ZNF8 ZRANB1	12 interacting genes: DDIT4L JAKMIP1 LRRK2 MCRS1 RNF4 SRPK1 SRPK2 SUMO1 SUMO1P1 SUMO2 TAX1BP1 UBE2I
Entrez ID		10445	147339
HPRD ID		11298	12690
Ensembl ID		ENSG00000187778	ENSG00000152242
Uniprot IDs		A0A024R134 Q96EZ8	Q96B23
PDB IDs
Enriched GO Terms of Interacting Partners?
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