CLEC4M and ICAM3

Data Source:
HPRD (in vitro)

		CLEC4M	ICAM3
Description		C-type lectin domain family 4 member M	intercellular adhesion molecule 3
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Integral Component Of Plasma Membrane Membrane Host Cell	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Virus Receptor Activity Protein Binding Mannose Binding Carbohydrate Binding ICAM-3 Receptor Activity Signaling Receptor Activity Peptide Antigen Binding Virion Binding Metal Ion Binding Calcium-dependent Protein Binding	Signaling Receptor Binding Integrin Binding Protein Binding
	Biological Process	Adaptive Immune Response Endocytosis Leukocyte Cell-cell Adhesion Cell-cell Recognition Modulation By Virus Of Host Process Virion Attachment To Host Cell Viral Genome Replication Antigen Processing And Presentation Intracellular Signal Transduction Innate Immune Response Viral Entry Into Host Cell Peptide Antigen Transport Intracellular Transport Of Virus	Stimulatory C-type Lectin Receptor Signaling Pathway Phagocytosis Cell Adhesion Extracellular Matrix Organization Regulation Of Immune Response Cell-cell Adhesion
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions CD209 (DC-SIGN) signaling
Drugs
Diseases
GWAS		Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 27863252) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) vWF levels ( 30586737) White blood cell count ( 32888494)	Crohn's disease ( 28067908 21102463) Inflammatory bowel disease ( 28067908) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031)
Interacting Genes		5 interacting genes: CD209 ICAM3 IFT20 ITGAM PLPP6	20 interacting genes: APP BRICD5 CD209 CLDN19 CLDN4 CLEC4M EDDM3B EZR ITGAD ITGAL ITGB2 MSN NINJ2 PRKCQ SEC22A SFTPC SMCO4 SMIM1 TSPO ZBTB16
Entrez ID		10332	3385
HPRD ID		12060	00889
Ensembl ID		ENSG00000104938	ENSG00000076662
Uniprot IDs		B4E2Z5 H7BXU4 Q9H2X3	A0A024R7C1 K7ERN2 P32942
PDB IDs		1K9J 1SL6 1XAR 1XPH 1Z0Y 3JQH	1T0P
Enriched GO Terms of Interacting Partners?
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