SF3A1 and RBM10

Data Source:
BioGRID (two hybrid, two hybrid, affinity chromatography technology)

		SF3A1	RBM10
Description		splicing factor 3a subunit 1	RNA binding motif protein 10
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP Nuclear Speck U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nuclear Speck Protein-containing Complex
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding MiRNA Binding Identical Protein Binding Metal Ion Binding
	Biological Process	MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing U2-type Prespliceosome Assembly	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Biological_process Negative Regulation Of Cell Population Proliferation Positive Regulation Of Smooth Muscle Cell Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome 3'-UTR-mediated MRNA Stabilization
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases			TARP syndrome
GWAS		Delirium ( 29631748) Eosinophil percentage of white cells ( 32888494) Urinary albumin-to-creatinine ratio ( 31511532)
Interacting Genes		60 interacting genes: APBB1 CSNK2A1 DDX42 GAS7 IL7R MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-2 MIR138-2 MIR141 MIR145 MIR155 MIR15A MIR15B MIR18A MIR18B MIR199A2 MIR19B1 MIR19B2 MIR200B MIR200C MIR20B MIR214 MIR221 MIR25 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR363 MIR451A MIR7-1 MIR7-3 MIR92A2 MIRLET7A1 MIRLET7A2 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I PRPF40A RBFOX2 RBM10 SF1 SF3A2 SF3A3 SMAD3 SMURF1 SP1 SUMO2 TCERG1 WBP4 WDR77	69 interacting genes: AKAP9 ATN1 BAHD1 BEND7 CASK CBLL1 CCAR1 CEP70 CPSF7 CSNK2A1 DDX17 DDX5 FAM124A GTSE1 HNRNPH2 HNRNPK HNRNPLL IK KHDRBS2 KLF1 MAPRE2 MBD6 MDM2 MEOX2 MIR106B MIR107 MIR128-1 MIR21 MIR214 MIRLET7A1 MIRLET7A3 MIRLET7D MIRLET7E MIRLET7G MIRLET7I NDEL1 NIN PATZ1 PCBP1 PRC1 PRCC PRDM14 PRR20A PTBP1 PTBP2 RBM12B RBM14 RBM4 RBMY1F SF1 SF3A1 SF3B2 SF3B4 SLAIN1 SNU13 SREK1 SRSF6 TBC1D22B THAP1 TLE5 U2AF1 UBQLN4 ZBTB24 ZFP64 ZNF275 ZNF317 ZNF408 ZNF473 ZNF526
Entrez ID		10291	8241
HPRD ID		06903	02095
Ensembl ID		ENSG00000099995	ENSG00000182872
Uniprot IDs		A0A024R1K8 Q15459	A0A0S2Z4W4 A0A0S2Z4X1 P98175 Q7Z3D7
PDB IDs		1ZKH 2DT6 2DT7 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6QX9 6Y53 6Y5Q	2LXI 2M2B 2MXV 2MXW 5ZSW 5ZSY
Enriched GO Terms of Interacting Partners?
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