SF3A1 and SF1

Data Source:
BioGRID (two hybrid, two hybrid)

		SF3A1	SF1
Description		splicing factor 3a subunit 1	splicing factor 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP Nuclear Speck U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Spliceosomal Complex Ribosome
	Molecular Function	RNA Binding Protein Binding	Transcription Corepressor Activity RNA Binding MRNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Pre-mRNA Branch Point Binding
	Biological Process	MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing U2-type Prespliceosome Assembly	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Negative Regulation Of Transcription, DNA-templated Regulation Of MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs			Artenimol
Diseases
GWAS		Delirium ( 29631748) Eosinophil percentage of white cells ( 32888494) Urinary albumin-to-creatinine ratio ( 31511532)	Mean reticulocyte volume ( 32888494) Urate levels ( 21768215)
Interacting Genes		60 interacting genes: APBB1 CSNK2A1 DDX42 GAS7 IL7R MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-2 MIR138-2 MIR141 MIR145 MIR155 MIR15A MIR15B MIR18A MIR18B MIR199A2 MIR19B1 MIR19B2 MIR200B MIR200C MIR20B MIR214 MIR221 MIR25 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR363 MIR451A MIR7-1 MIR7-3 MIR92A2 MIRLET7A1 MIRLET7A2 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I PRPF40A RBFOX2 RBM10 SF1 SF3A2 SF3A3 SMAD3 SMURF1 SP1 SUMO2 TCERG1 WBP4 WDR77	58 interacting genes: APBB1 ATXN1 BCAS2 BCL2 CDC42 CIAO1 DDX17 DUX4L9 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MIR106B MIR155 MIR19B2 MIR34A MIRLET7G MKRN3 NCK2 NFKB1 OSTF1 PLSCR1 PRKG1 PRPF40A PSMA3 PUF60 RBM10 RBM17 RBM4 RBM7 RBPMS SEC23A SF3A1 SF3B1 SF3B4 TAF15 TCERG1 TNPO2 TRIM23 TRIM69 TTN TXNL4B U2AF2 UBL5 WBP4 WDR77 WDR83 WWP2 ZNF461
Entrez ID		10291	7536
HPRD ID		06903	03306
Ensembl ID		ENSG00000099995	ENSG00000168066
Uniprot IDs		A0A024R1K8 Q15459	A0A024R566 A0A024R572 A0A024R588 A0A024R5D9 B4DX42 Q15637
PDB IDs		1ZKH 2DT6 2DT7 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6QX9 6Y53 6Y5Q	1K1G 1O0P 1OPI 2M09 2M0G 4FXW 4FXX
Enriched GO Terms of Interacting Partners?
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