RAMP1 and NKG7

Data Source:
BioGRID (two hybrid)

		RAMP1	NKG7
Description		receptor activity modifying protein 1	natural killer cell granule protein 7
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex Amylin Receptor Complex 1 CGRP Receptor Complex	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Calcitonin Gene-related Peptide Receptor Activity Protein Binding Coreceptor Activity Amylin Receptor Activity Calcitonin Gene-related Peptide Binding	Protein Binding
	Biological Process	Angiogenesis Calcium Ion Transport Intracellular Protein Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Protein Transport Receptor Internalization Positive Regulation Of Protein Binding Cellular Response To Hormone Stimulus Positive Regulation Of Protein Glycosylation Protein Localization To Plasma Membrane Amylin Receptor Signaling Pathway Calcitonin Gene-related Peptide Receptor Signaling Pathway
Pathways		G alpha (s) signalling events Calcitonin-like ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs		Pramlintide
Diseases
GWAS		Obesity-related traits ( 23251661) Resting metabolic rate ( 28476931)	Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		9 interacting genes: CALCA CALCR CALCRL IAPP MAL MS4A13 NKG7 SLC31A2 VIPR1	45 interacting genes: AGTRAP AMIGO1 AQP6 ARL13B ATP6AP2 BAMBI CD53 CD79A CLDN7 CLEC2D CLEC4E CLSTN3 CREB3 EBP EDA2R ERGIC3 FAM210B FFAR2 FNDC9 GJA5 GORAB GPX8 ISLR2 KLRC1 LHFPL5 LMNA MFSD6 MGST3 MS4A3 MSR1 MUC1 OPRK1 PEX12 RAMP1 RNF24 SLC18A2 SLC30A8 STOM STX1A TLCD4 TMEM106C TMEM130 TMEM139 TMEM80 TMEM88
Entrez ID		10267	4818
HPRD ID		05515	16188
Ensembl ID		ENSG00000132329	ENSG00000105374
Uniprot IDs		E9PC20 O60894	Q16617
PDB IDs		2YX8 3N7P 3N7R 3N7S 4RWG 5V6Y 6D1U 6E3Y 6UMG 6ZHO 6ZIS
Enriched GO Terms of Interacting Partners?
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