TENM1 and APBB1

Data Source:
BioGRID (two hybrid)

		TENM1	APBB1
Description		teneurin transmembrane protein 1	amyloid beta precursor protein binding family B member 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytoskeleton Plasma Membrane Integral Component Of Plasma Membrane Nuclear Matrix Nuclear Speck Neuron Projection Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Plasma Membrane Nuclear Speck Lamellipodium Growth Cone Synapse
	Molecular Function	Heparin Binding Protein Homodimerization Activity Protein Heterodimerization Activity Cell Adhesion Molecule Binding	Amyloid-beta Binding Chromatin Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding Ubiquitin Protein Ligase Binding Histone Binding Low-density Lipoprotein Particle Receptor Binding Proline-rich Region Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase III Immune Response Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Neuropeptide Signaling Pathway Nervous System Development Negative Regulation Of Cell Population Proliferation Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of MAP Kinase Activity Neuron Development Positive Regulation Of Filopodium Assembly Positive Regulation Of Intracellular Protein Transport	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Apoptotic Process Cellular Response To DNA Damage Stimulus Cell Cycle Arrest Signal Transduction Axonogenesis Negative Regulation Of Cell Growth Positive Regulation Of Apoptotic Process Histone H4 Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Secretion
Pathways			Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Drugs
Diseases
GWAS			Blood protein levels ( 29875488) Malaria ( 31844061)
Interacting Genes		12 interacting genes: APBB1 BEX1 CSNK2B FIBP MACF1 MBD1 NUBP1 PICALM POLR2J PTPN12 RACK1 SORBS1	69 interacting genes: ABI1 ABL1 ANXA1 APLP1 APLP2 APP ARF6 ATXN1 ATXN1L CCDC97 CHERP CLSTN1 CPSF6 CPSF7 CYFIP1 CYFIP2 DDX17 DDX3X DDX46 DHX15 DHX9 DIAPH1 DIAPH2 EGFR ELMO1 ENAH ERBB2 EVL FASLG HNRNPH1 HNRNPK HTATSF1 KAT5 KHDRBS1 KHSRP LRP1 LRP2 NONO PABPC1 PQBP1 PRNP PTBP1 RBM17 RPL4 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ TENM1 TFCP2 THRAP3 TSHZ1 TSHZ2 TSHZ3 U2AF2 VASP WAS WASF2 WASL WBP11 WIPF1 WIPF2 YBX1 YLPM1
Entrez ID		10178	322
HPRD ID		06669	04087
Ensembl ID		ENSG00000009694	ENSG00000166313
Uniprot IDs		B7ZMH4 Q9UKZ4	B7Z4M9 O00213
PDB IDs			2E45 2HO2 2IDH 2OEI 3D8D 3D8E 3D8F 3DXC 3DXD 3DXE 5NQH
Enriched GO Terms of Interacting Partners?
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