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APBB1 and CPSF7
Data Source:
BioGRID
(pull down)
APBB1
CPSF7
Description
amyloid beta precursor protein binding family B member 1
cleavage and polyadenylation specific factor 7
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Plasma Membrane
Nuclear Speck
Lamellipodium
Growth Cone
Synapse
Nucleus
Nucleoplasm
Cytoplasm
MRNA Cleavage And Polyadenylation Specificity Factor Complex
MRNA Cleavage Factor Complex
Membrane
Molecular Function
Amyloid-beta Binding
Chromatin Binding
Transcription Coactivator Activity
Protein Binding
Transcription Factor Binding
Ubiquitin Protein Ligase Binding
Histone Binding
Low-density Lipoprotein Particle Receptor Binding
Proline-rich Region Binding
RNA Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription, DNA-templated
Apoptotic Process
Cellular Response To DNA Damage Stimulus
Cell Cycle Arrest
Signal Transduction
Axonogenesis
Negative Regulation Of Cell Growth
Positive Regulation Of Apoptotic Process
Histone H4 Acetylation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Protein Secretion
MRNA Splicing, Via Spliceosome
Termination Of RNA Polymerase II Transcription
MRNA 3'-end Processing
Protein Tetramerization
Protein Heterotetramerization
Pre-mRNA Cleavage Required For Polyadenylation
MRNA Alternative Polyadenylation
Messenger Ribonucleoprotein Complex Assembly
Pathways
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
Blood protein levels (
29875488
)
Malaria (
31844061
)
Interacting Genes
69 interacting genes:
ABI1
ABL1
ANXA1
APLP1
APLP2
APP
ARF6
ATXN1
ATXN1L
CCDC97
CHERP
CLSTN1
CPSF6
CPSF7
CYFIP1
CYFIP2
DDX17
DDX3X
DDX46
DHX15
DHX9
DIAPH1
DIAPH2
EGFR
ELMO1
ENAH
ERBB2
EVL
FASLG
HNRNPH1
HNRNPK
HTATSF1
KAT5
KHDRBS1
KHSRP
LRP1
LRP2
NONO
PABPC1
PQBP1
PRNP
PTBP1
RBM17
RPL4
SF1
SF3A1
SF3A2
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
TENM1
TFCP2
THRAP3
TSHZ1
TSHZ2
TSHZ3
U2AF2
VASP
WAS
WASF2
WASL
WBP11
WIPF1
WIPF2
YBX1
YLPM1
59 interacting genes:
APBB1
ARMC7
ATXN1
CATSPER1
CFAP206
CLK2
CSNK2A1
DVL2
EPM2AIP1
EWSR1
GAS8
GCC1
GRB2
GUCD1
HINT1
HNRNPF
ITCH
LENG8
LNX1
MIR1-1
MIR1-2
MIR10B
MIR128-2
MIR141
MIR155
MIR16-1
MIR17
MIR18B
MIR199A1
MIR19A
MIR19B1
MIR25
MIR29C
MIR34B
MIR7-1
MIR9-2
MIR93
MIRLET7B
NCK2
NUDT21
PATZ1
PID1
PRKAA2
PRMT2
RBM10
RUNX1T1
SEC23B
SMAD3
SNRNP25
SNX18
SORBS3
SPG21
SRPK2
SUMO2
TLE5
TNS2
U2AF2
WBP4
WWOX
Entrez ID
322
79869
HPRD ID
04087
16906
Ensembl ID
ENSG00000166313
ENSG00000149532
Uniprot IDs
B7Z4M9
O00213
B4DGF8
Q8N684
PDB IDs
2E45
2HO2
2IDH
2OEI
3D8D
3D8E
3D8F
3DXC
3DXD
3DXE
5NQH
3N9U
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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