GJC1 and TJP3

Data Source:
HPRD (two hybrid)

		GJC1	TJP3
Description		gap junction protein gamma 1	tight junction protein 3
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Gap Junction Connexin Complex Intercalated Disc Integral Component Of Membrane Synapse	Nucleus Nucleoplasm Plasma Membrane Bicellular Tight Junction Cell Junction
	Molecular Function	Ion Channel Activity Gap Junction Channel Activity Protein Binding Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling	Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Vasculogenesis Muscle Contraction Cell-cell Junction Assembly Cell-cell Signaling Chemical Synaptic Transmission Visual Perception Gap Junction Assembly Ion Transmembrane Transport Cell Development Cardiac Muscle Tissue Development Atrial Cardiac Muscle Cell Action Potential SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling	Maintenance Of Blood-brain Barrier Cell-cell Junction Organization Establishment Of Endothelial Intestinal Barrier Cell-cell Adhesion Protein Localization To Cell-cell Junction Positive Regulation Of Blood-brain Barrier Permeability
Pathways		Electric Transmission Across Gap Junctions Gap junction assembly
Drugs
Diseases
GWAS			Cleft lip with or without cleft palate x maternal periconceptional vitamin use interaction (parent of origin effect) ( 31372216)
Interacting Genes		8 interacting genes: APOL3 CNST MEOX2 SLC66A1 TJP1 TJP3 TMEM86A UBQLN4	5 interacting genes: CLDN1 FASLG GJC1 PATJ TJP1
Entrez ID		10052	27134
HPRD ID		08819	18194
Ensembl ID		ENSG00000182963	ENSG00000105289
Uniprot IDs		A0A654IDC0 P36383	O95049
PDB IDs		3SHW	3KFV
Enriched GO Terms of Interacting Partners?
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