CHAF1A and ASF1A

Data Source:
HPRD (in vivo)

		CHAF1A	ASF1A
Description		chromatin assembly factor 1 subunit A	anti-silencing function 1A histone chaperone
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Protein-containing Complex CAF-1 Complex	Chromatin Nucleus Nucleoplasm Protein-containing Complex
	Molecular Function	Chromatin Binding Protein Binding Identical Protein Binding Unfolded Protein Binding Chromo Shadow Domain Binding	Chromatin Binding Protein Binding Histone Binding
	Biological Process	DNA Replication DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly Cell Cycle Chromatin Assembly	Osteoblast Differentiation DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Negative Regulation Of Chromatin Silencing Muscle Cell Differentiation
Pathways			Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)	Mean platelet volume ( 32888494) Multiple sclerosis ( 31604244) QT interval ( 19305408)
Interacting Genes		47 interacting genes: ANP32A ANP32B ASF1A ASF1B BLM CBX1 CBX5 CDC7 CDK2 CHAF1B CREBBP DBF4 DDX41 H3-4 H3C6 HMGB2 LZTR1 MBD1 MEI4 MSH6 NOTO PABPC1 PAX6 PCBD2 PCNA POU6F2 RBFOX2 REL SERTAD1 SET SPOP STAT5B SUMO1 SUMO2 SUMO3 TCERG1 TCF4 TRIB3 TRIM28 XRCC5 XRCC6 YWHAB YWHAE YWHAG YWHAQ ZNF408 ZNF620	35 interacting genes: ASF1B CDAN1 CHAF1A CHAF1B CHEK2 H3-3A H3-4 H3C3 H3C6 H4-16 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HIRA HTATIP2 MCM2 NASP PAFAH1B2 PRR3 ST13 TAF1 TLK1 TLK2 VPS28 ZDHHC17
Entrez ID		10036	25842
HPRD ID		03148	16459
Ensembl ID		ENSG00000167670	ENSG00000111875
Uniprot IDs		Q13111	Q9Y294
PDB IDs			1TEY 2I32 2IIJ 2IO5 3AAD 5C3I 6F0F 6F0G 6F0H
Enriched GO Terms of Interacting Partners?
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