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RAD17

Description RAD17 checkpoint clamp loader component
Image No pdb structure
GO Annotations Cellular Component
  • Chromosome, Telomeric Region
  • Nucleus
  • Nucleoplasm
  • Nucleolus
  • Rad17 RFC-like Complex
Molecular Function
  • Chromatin Binding
  • DNA Clamp Loader Activity
  • Protein Binding
  • ATP Binding
Biological Process
  • DNA Replication Checkpoint
  • DNA Damage Checkpoint
  • DNA Replication
  • DNA Repair
  • Cellular Response To DNA Damage Stimulus
  • Negative Regulation Of DNA Replication
  • Intra-S DNA Damage Checkpoint
  • Mitotic DNA Replication Checkpoint
  • Regulation Of Phosphorylation
  • Regulation Of Signal Transduction By P53 Class Mediator
Pathways
  • Activation of ATR in response to replication stress
  • HDR through Single Strand Annealing (SSA)
  • Processing of DNA double-strand break ends
  • Presynaptic phase of homologous DNA pairing and strand exchange
  • Regulation of TP53 Activity through Phosphorylation
  • G2/M DNA damage checkpoint
Drugs
Diseases
GWAS
  • Blood urea nitrogen levels ( 31152163)
Novel Interacting Genes 1 novel interacting genes: F2RL1
Interacting Genes 15 interacting genes: ATM ATR HUS1 MCM7 POLE PRKDC PRMT6 RAD1 RAD9A RAD9B RFC2 RFC3 RFC4 SNU13 USP20
Entrez ID 5884
HPRD ID 09124
Ensembl ID ENSG00000152942
Uniprot IDs O75943
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025