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SLX1A

Description SLX1 homolog A, structure-specific endonuclease subunit
Image No pdb structure
GO Annotations Cellular Component
  • Nucleoplasm
  • Slx1-Slx4 Complex
Molecular Function
  • Protein Binding
  • Crossover Junction Endodeoxyribonuclease Activity
  • 5'-flap Endonuclease Activity
  • Metal Ion Binding
Biological Process
  • Double-strand Break Repair Via Homologous Recombination
  • DNA Repair
  • DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing
  • Telomere Maintenance Via Telomere Lengthening
  • Interstrand Cross-link Repair
  • Telomeric D-loop Disassembly
  • Nucleic Acid Phosphodiester Bond Hydrolysis
  • T-circle Formation
  • Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
  • Positive Regulation Of T-circle Formation
Pathways
  • Resolution of D-loop Structures through Holliday Junction Intermediates
  • Fanconi Anemia Pathway
Drugs
Diseases
GWAS
  • Brain morphology (MOSTest) ( 32665545)
Interacting Genes 6 interacting genes: EME1 ERCC1 ERCC4 GRB2 MUS81 SLX4
Entrez ID 548593
HPRD ID 18681
Ensembl ID ENSG00000132207
Uniprot IDs Q9BQ83
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025