IL17A

Description		interleukin 17A
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space External Side Of Plasma Membrane
	Molecular Function	Cytokine Activity Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Positive Regulation Of Antimicrobial Peptide Production Adaptive Immune Response Apoptotic Process Inflammatory Response Immune Response Cell-cell Signaling Cell Death Cytokine-mediated Signaling Pathway Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-12 Production Positive Regulation Of Interleukin-16 Production Positive Regulation Of Interleukin-23 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Innate Immune Response Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Defense Response To Fungus Intestinal Epithelial Structure Maintenance Cellular Response To Interleukin-1 Fibroblast Activation Interleukin-17-mediated Signaling Pathway Granulocyte Migration Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Bicellular Tight Junction Assembly Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production
Pathways		Interleukin-17 signaling Interleukin-4 and Interleukin-13 signaling
Drugs		Secukinumab Ixekizumab
Diseases
GWAS		Height ( 28552196)
Interacting Genes		3 interacting genes: DPH2 IL17RA KCNIP4
Entrez ID		3605
HPRD ID		04396
Ensembl ID		ENSG00000112115
Uniprot IDs		Q16552
PDB IDs		2VXS 4HR9 4HSA 4QHU 5HHV 5HHX 5HI3 5HI4 5HI5 5N7W 5N92 5NAN 5VB9 6WIO 6WIR
Enriched GO Terms of Interacting Partners?
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