HCRT

Description		hypocretin neuropeptide precursor
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GO Annotations	Cellular Component	Extracellular Region Rough Endoplasmic Reticulum Synaptic Vesicle Secretory Granule Perinuclear Region Of Cytoplasm Postsynapse
	Molecular Function	Neuropeptide Hormone Activity Type 1 Hypocretin Receptor Binding Type 2 Hypocretin Receptor Binding
	Biological Process	Temperature Homeostasis G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Chemical Synaptic Transmission Negative Regulation Of DNA Replication Sleep Response To Starvation Eating Behavior Negative Regulation Of Potassium Ion Transport Regulation Of Neurotransmitter Secretion Positive Regulation Of Calcium Ion Transport Negative Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Transmission Of Nerve Impulse Excitatory Postsynaptic Potential Positive Regulation Of Cold-induced Thermogenesis
Pathways		Orexin and neuropeptides FF and QRFP bind to their respective receptors G alpha (q) signalling events
Drugs		Pidolic acid
Diseases
GWAS
Interacting Genes		3 interacting genes: HCRTR1 HCRTR2 NPFFR2
Entrez ID		3060
HPRD ID		03836
Ensembl ID		ENSG00000161610
Uniprot IDs		O43612
PDB IDs		1CQ0 1R02 1UVQ 1WSO
Enriched GO Terms of Interacting Partners?
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