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CIT
Description
citron rho-interacting serine/threonine kinase
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Cytoskeleton
Membrane
Molecular Function
Transcription Coactivator Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
SH3 Domain Binding
Protein Kinase Binding
PDZ Domain Binding
Protein Serine/threonine Kinase Inhibitor Activity
Metal Ion Binding
Scaffold Protein Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Mitotic Cell Cycle
Mitotic Cytokinesis
Peptidyl-threonine Phosphorylation
Actomyosin Structure Organization
Positive Regulation Of Cytokinesis
Negative Regulation Of Hippo Signaling
Intracellular Signal Transduction
Generation Of Neurons
Neuron Apoptotic Process
Negative Regulation Of Protein Serine/threonine Kinase Activity
Pathways
RHO GTPases activate CIT
RHO GTPases activate CIT
Drugs
Fostamatinib
Diseases
GWAS
Number of sexual partners (
30643258
)
Urgency urinary incontinence (
25524241
)
Novel Interacting Genes
6 novel interacting genes:
ABCB9
DERA
ENPP7
HIP1R
MLXIPL
SELPLG
Interacting Genes
10 interacting genes:
DISC1
DLG4
GRIN1
GRIN2D
MTNR1A
RAC1
RHOA
RHOB
RHOC
RND3
Entrez ID
11113
HPRD ID
09289
Ensembl ID
ENSG00000122966
Uniprot IDs
O14578
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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