Influenza - Wiki-CORONA

Symbols	Name 1	Name 2	Pathways 1 Hide	Pathways 2 Hide	Drugs 1 Hide	Drugs 2 Hide	Diseases 1 Hide	Diseases 2 Hide
ERBB4 and PTPRR	erb-b2 receptor tyrosine kinase 4	protein tyrosine phosphatase receptor type R			Afatinib Brigatinib
ERBB4 and NRG3	erb-b2 receptor tyrosine kinase 4	neuregulin 3		Signaling by ERBB2 Signaling by ERBB4 SHC1 events in ERBB2 signaling SHC1 events in ERBB2 signaling PI3K events in ERBB4 signaling SHC1 events in ERBB4 signaling Nuclear signaling by ERBB4 PIP3 activates AKT signaling GRB2 events in ERBB2 signaling PI3K events in ERBB2 signaling Constitutive Signaling by Aberrant PI3K in Cancer RAF/MAP kinase cascade ERBB2 Regulates Cell Motility PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling ERBB2 Activates PTK6 Signaling Downregulation of ERBB2 signaling Signaling by ERBB2 KD Mutants Signaling by ERBB2 TMD/JMD mutants	Afatinib Brigatinib
ERG and NUMA1	ETS transcription factor ERG	nuclear mitotic apparatus protein 1		Recruitment of NuMA to mitotic centrosomes Mitotic Prophase			Ewing's sarcoma Prostate cancer
ETS1 and GATA3	ETS proto-oncogene 1, transcription factor	GATA binding protein 3	Oncogene Induced Senescence	Ub-specific processing proteases Interleukin-4 and Interleukin-13 signaling RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression Factors involved in megakaryocyte development and platelet production
ETS2 and GATA3	ETS proto-oncogene 2, transcription factor	GATA binding protein 3	Oncogene Induced Senescence	Ub-specific processing proteases Interleukin-4 and Interleukin-13 signaling RUNX1 regulates transcription of genes involved in differentiation of HSCs Estrogen-dependent gene expression Factors involved in megakaryocyte development and platelet production
F2R and PDCD6IP	coagulation factor II thrombin receptor	programmed cell death 6 interacting protein	Common Pathway of Fibrin Clot Formation Peptide ligand-binding receptors G alpha (q) signalling events Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs)	Budding and maturation of HIV virion Uptake and function of anthrax toxins	Streptokinase SR-123781A Vorapaxar Thrombin
F2RL1 and NUMA1	F2R like trypsin receptor 1	nuclear mitotic apparatus protein 1	Peptide ligand-binding receptors G alpha (q) signalling events	Recruitment of NuMA to mitotic centrosomes Mitotic Prophase
ACSL3 and TAS2R14	acyl-CoA synthetase long chain family member 3	taste 2 receptor member 14	Intracellular metabolism of fatty acids regulates insulin secretion Synthesis of very long-chain fatty acyl-CoAs	G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors)	Icosapent
ACSL3 and NDRG1	acyl-CoA synthetase long chain family member 3	N-myc downstream regulated 1	Intracellular metabolism of fatty acids regulates insulin secretion Synthesis of very long-chain fatty acyl-CoAs	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	Icosapent			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
ACSL3 and MAP2	acyl-CoA synthetase long chain family member 3	microtubule associated protein 2	Intracellular metabolism of fatty acids regulates insulin secretion Synthesis of very long-chain fatty acyl-CoAs		Icosapent	Estramustine Paclitaxel Docetaxel
ACSL3 and SMARCAL1	acyl-CoA synthetase long chain family member 3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1	Intracellular metabolism of fatty acids regulates insulin secretion Synthesis of very long-chain fatty acyl-CoAs		Icosapent
ACSL3 and MMP13	acyl-CoA synthetase long chain family member 3	matrix metallopeptidase 13	Intracellular metabolism of fatty acids regulates insulin secretion Synthesis of very long-chain fatty acyl-CoAs	Collagen degradation Collagen degradation Degradation of the extracellular matrix Degradation of the extracellular matrix Activation of Matrix Metalloproteinases Assembly of collagen fibrils and other multimeric structures RUNX2 regulates genes involved in cell migration	Icosapent	Marimastat 3-Methylpyridine 2-{4-[4-(4-Chloro-Phenoxy)-Benzenesulfonyl]-Tetrahydro-Pyran-4-Yl}-N-Hydroxy-Acetamide WAY-151693 Hydroxyaminovaline 1-Methyloxy-4-Sulfone-Benzene PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-(3-METHYL-BENZYLAMIDE) PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-(4-FLUORO-3-METHYL-BENZYLAMIDE) PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-[(PYRIDIN-3-YLMETHYL)-AMIDE] TERT-BUTYL 4-({[4-(BUT-2-YN-1-YLAMINO)PHENYL]SULFONYL}METHYL)-4-[(HYDROXYAMINO)CARBONYL]PIPERIDINE-1-CARBOXYLATE 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLPROP-1-YN-1-YL)-1,4-DIHYDROQUINAZOLIN-3(2H)-YL]METHYL}BENZOIC ACID 5-(2-ETHOXYETHYL)-5-[4-(4-FLUOROPHENOXY)PHENOXY]PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE CTS-1027 BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIAZOLO[3,2-C]PYRIMIDINE-2-CARBOXYLATE		Metaphyseal dysplasias, including: Metaphyseal dysplasia, Schmid type; Metaphyseal dysplasia, McKusik type; Metaphyseal dysplasia, Jansen type; Shwachman-Bodian-Diamond syndrome (SBDS); Metaphyseal anadysplasia (MAD)
PTK2B and PDCD6IP	protein tyrosine kinase 2 beta	programmed cell death 6 interacting protein	Signal regulatory protein family interactions VEGFA-VEGFR2 Pathway Interleukin-2 signaling	Budding and maturation of HIV virion Uptake and function of anthrax toxins	Leflunomide Genistein 4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide Baricitinib
FCN1 and TGFB1	ficolin 1	transforming growth factor beta 1	Lectin pathway of complement activation Initial triggering of complement Ficolins bind to repetitive carbohydrate structures on the target cell surface Neutrophil degranulation	Platelet degranulation Influenza Virus Induced Apoptosis Cell surface interactions at the vascular wall Molecules associated with elastic fibres Downregulation of TGF-beta receptor signaling Downregulation of TGF-beta receptor signaling TGF-beta receptor signaling activates SMADs TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) Syndecan interactions ECM proteoglycans SMAD2/3 Phosphorylation Motif Mutants in Cancer TGFBR2 MSI Frameshift Mutants in Cancer TGFBR2 Kinase Domain Mutants in Cancer TGFBR1 KD Mutants in Cancer TGFBR1 LBD Mutants in Cancer Transcriptional regulation of white adipocyte differentiation UCH proteinases Interleukin-4 and Interleukin-13 signaling RUNX3 regulates CDKN1A transcription Regulation of RUNX3 expression and activity RUNX3 regulates p14-ARF		Hyaluronidase Hyaluronidase (Human Recombinant)		Graft-versus-host disease Allograft rejection Camurati-Engelmann disease; Progressive diaphyseal dysplasia
FGF12 and COIL	fibroblast growth factor 12	coilin	Phase 0 - rapid depolarisation
FGF12 and SMURF1	fibroblast growth factor 12	SMAD specific E3 ubiquitin protein ligase 1	Phase 0 - rapid depolarisation	Signaling by BMP Downregulation of TGF-beta receptor signaling TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) Asymmetric localization of PCP proteins Hedgehog 'on' state Hedgehog 'on' state Regulation of RUNX2 expression and activity Regulation of RUNX2 expression and activity Regulation of RUNX3 expression and activity Antigen processing: Ubiquitination & Proteasome degradation
FGF12 and MAPK13	fibroblast growth factor 12	mitogen-activated protein kinase 13	Phase 0 - rapid depolarisation	NOD1/2 Signaling Pathway p38MAPK events DSCAM interactions VEGFA-VEGFR2 Pathway		KC706
FGF12 and PJA1	fibroblast growth factor 12	praja ring finger ubiquitin ligase 1	Phase 0 - rapid depolarisation	Antigen processing: Ubiquitination & Proteasome degradation
FGF12 and ZNF460	fibroblast growth factor 12	zinc finger protein 460	Phase 0 - rapid depolarisation	Generic Transcription Pathway
FGF12 and YWHAE	fibroblast growth factor 12	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon	Phase 0 - rapid depolarisation	Activation of BAD and translocation to mitochondria Translocation of SLC2A4 (GLUT4) to the plasma membrane Signaling by Hippo NADE modulates death signalling Regulation of PLK1 Activity at G2/M Transition Regulation of HSF1-mediated heat shock response HSF1 activation Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane RHO GTPases activate PKNs TP53 Regulates Metabolic Genes Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex AURKA Activation by TPX2 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models RAB GEFs exchange GTP for GDP on RABs		Fusicoccin Phenethyl Isothiocyanate		Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)

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